日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Profiling the Tox21 Compound Library for Their Inhibitory Effects on Cytochrome P450 Enzymes

对 Tox21 化合物库进行分析,以评估其对细胞色素 P450 酶的抑制作用

Sakamuru, Srilatha; Travers, Jameson; Klumpp-Thomas, Carleen; Huang, Ruili; Witt, Kristine L; Ferguson, Stephen S; Simmons, Steven O; Reif, David M; Simeonov, Anton; Xia, Menghang

Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT)

评估历史阴性对照数据的质量并合理利用这些数据:国际遗传毒性测试研讨会(IWGT)报告

Dertinger, Stephen D; Li, Dingzhou; Beevers, Carol; Douglas, George R; Heflich, Robert H; Lovell, David P; Roberts, Daniel J; Smith, Robert; Uno, Yoshifumi; Williams, Andrew; Witt, Kristine L; Zeller, Andreas; Zhou, Changhui

Within-laboratory reproducibility of Ames test results: Are repeat tests necessary?

Ames 测试结果的实验室内重复性:是否需要重复测试?

Zeiger, Errol; Mitchell, Constance A; Pfuhler, Stefan; Liao, Yang; Witt, Kristine L

Next Generation Sequencing Workshop at the Royal Society of Medicine (London, May 2022): how genomics is on the path to modernizing genetic toxicology

英国皇家医学会下一代测序研讨会(伦敦,2022年5月):基因组学如何引领遗传毒理学现代化

Lynch, Anthony M; Zanoni, Thalita B; Salk, Jesse J; Martincorena, Inigo; Young, Robert R; Kucab, Jill; Valentine, Charles C; Yauk, Carole; Escobar, Patricia A; Witt, Kristine L; Frötschl, Roland; Reed, Simon H; Ashford, Anne

Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency

纠错双链测序技术能够直接检测和定量人TK6细胞中的突变,且具有很高的实验室间一致性。

Cho, Eunnara; Swartz, Carol D; Williams, Andrew; V Rivas, Miriam; Recio, Leslie; Witt, Kristine L; Schmidt, Elizabeth K; Yaplee, Jeffry; Smith, Thomas H; Van, Phu; Lo, Fang Yin; Valentine, Charles C 3rd; Salk, Jesse J; Marchetti, Francesco; Smith-Roe, Stephanie L; Yauk, Carole L

The genotoxicity potential of luteolin is enhanced by CYP1A1 and CYP1A2 in human lymphoblastoid TK6 cells

木犀草素在人淋巴母细胞TK6细胞中的遗传毒性可通过CYP1A1和CYP1A2增强。

Li, Xilin; He, Xiaobo; Chen, Si; Le, Yuan; Bryant, Matthew S; Guo, Lei; Witt, Kristine L; Mei, Nan

Evaluation of 2-methoxy-4-nitroaniline (MNA) in hypersensitivity, 14-day subacute, reproductive, and genotoxicity studies

对 2-甲氧基-4-硝基苯胺 (MNA) 进行超敏反应、14 天亚急性毒性、生殖毒性和遗传毒性研究。

Frawley, Rachel P; Witt, Kristine L; Cunny, Helen; Germolec, Dori R; Jackson-Humbles, Daven; Malarkey, David; Shockley, Keith R; Stout, Matthew; Travlos, Greg; Buccellato, Matthew; Fallacara, Dawn; Harris, Shawn; Kissling, Grace E; Manheng, Wimolnut; Surh, Irene Inok; White, Kimber Jr; Auerbach, Scott S

Corrigendum to: "Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing"

更正: “用于基因毒性测试的表达人类细胞色素P450的TK6衍生细胞的开发和应用”

Li, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G; Zhou, Tong; Witt, Kristine L; Mei, Nan

Development and Application of TK6-derived Cells Expressing Human Cytochrome P450s for Genotoxicity Testing

开发和应用表达人细胞色素P450的TK6衍生细胞进行基因毒性测试

Li, Xilin; Chen, Si; Guo, Xiaoqing; Wu, Qiangen; Seo, Ji-Eun; Guo, Lei; Manjanatha, Mugimane G; Zhou, Tong; Witt, Kristine L; Mei, Nan

Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure

亚慢性暴露后,评估手机射频辐射对雄性和雌性大鼠和小鼠的遗传毒性

Smith-Roe, Stephanie L; Wyde, Michael E; Stout, Matthew D; Winters, John W; Hobbs, Cheryl A; Shepard, Kim G; Green, Amanda S; Kissling, Grace E; Shockley, Keith R; Tice, Raymond R; Bucher, John R; Witt, Kristine L