日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
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2025
2026
影响因子:
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The novel persistent sodium current inhibitor PRAX-562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers.

新型持续性钠电流抑制剂 PRAX-562 具有强效抗惊厥活性，与标准钠通道阻滞剂相比，其保护指数有所提高

期刊:Epilepsia
影响因子:6.6
doi:10.1111/epi.17149
Kahlig Kristopher M, Scott Liam, Hatch Robert J, Griffin Andrew, Martinez Botella Gabriel, Hughes Zoë A, Wittmann Marion
信号转导
发表日期：2022
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Discovery of the First Orally Available, Selective K(Na)1.1 Inhibitor: In Vitro and In Vivo Activity of an Oxadiazole Series

首个口服选择性K(Na)1.1抑制剂的发现：恶二唑系列化合物的体外和体内活性

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.0c00675
Griffin, Andrew M; Kahlig, Kristopher M; Hatch, Robert John; Hughes, Zoë A; Chapman, Mark L; Antonio, Brett; Marron, Brian E; Wittmann, Marion; Martinez-Botella, Gabriel
发表日期：2021
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MK-7622: A First-in-Class M(1) Positive Allosteric Modulator Development Candidate

MK-7622：首创的M(1)正向变构调节剂候选药物

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.8b00095
Beshore, Douglas C; N Di Marco, Christina; Chang, Ronald K; Greshock, Thomas J; Ma, Lei; Wittmann, Marion; Seager, Matthew A; Koeplinger, Kenneth A; Thompson, Charles D; Fuerst, Joy; Hartman, George D; Bilodeau, Mark T; Ray, William J; Kuduk, Scott D
发表日期：2018
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Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction

强效PDZ结构域PICK1抑制剂可调节淀粉样蛋白β介导的突触功能障碍

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-018-31680-3
Lin, Edward Y S; Silvian, Laura F; Marcotte, Douglas J; Banos, Charles C; Jow, Flora; Chan, Timothy R; Arduini, Robert M; Qian, Fang; Baker, Darren P; Bergeron, Chris; Hession, Catherine A; Huganir, Richard L; Borenstein, Cassandra F; Enyedy, Istvan; Zou, Jinming; Rohde, Ellen; Wittmann, Marion; Kumaravel, Gnanasambandam; Rhodes, Kenneth J; Scannevin, Robert H; Dunah, Anthone W; Guckian, Kevin M
PICK1
神经科学
发表日期：2018
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Confronting species distribution model predictions with species functional traits

将物种分布模型预测与物种功能性状进行比较

期刊:Ecology and Evolution
影响因子:2.3
doi:10.1002/ece3.1898
Wittmann, Marion E; Barnes, Matthew A; Jerde, Christopher L; Jones, Lisa A; Lodge, David M
发表日期：2016
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Using structured expert judgment to assess invasive species prevention: Asian carp and the Mississippi-Great Lakes hydrologic connection

运用结构化的专家判断评估入侵物种预防：亚洲鲤鱼与密西西比河-五大湖水文联系

期刊:Environmental Science & Technology
影响因子:11.3
doi:10.1021/es4043098
Wittmann, Marion E; Cooke, Roger M; Rothlisberger, John D; Lodge, David M
发表日期：2014
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Out-of-sample validation for structured expert judgment of Asian carp establishment in Lake Erie

对亚洲鲤鱼在伊利湖建立种群的结构化专家判断进行样本外验证

期刊:Integrated Environmental Assessment and Management
影响因子:8.4
doi:10.1002/ieam.1559
Cooke, Roger M; Wittmann, Marion E; Lodge, David M; Rothlisberger, John D; Rutherford, Edward S; Zhang, Hongyan; Mason, Doran M
发表日期：2014
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Geographic selection bias of occurrence data influences transferability of invasive Hydrilla verticillata distribution models

地理选择偏差会影响入侵物种轮叶黑藻分布模型的可移植性。

期刊:Ecology and Evolution
影响因子:2.3
doi:10.1002/ece3.1120
Barnes, Matthew A; Jerde, Christopher L; Wittmann, Marion E; Chadderton, W Lindsay; Ding, Jianqing; Zhang, Jialiang; Purcell, Matthew; Budhathoki, Milan; Lodge, David M
发表日期：2014
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Identification of amides as carboxylic Acid surrogates for quinolizidinone-based m1 positive allosteric modulators

鉴定酰胺类化合物作为喹诺里酮类m1正向变构调节剂的羧酸替代物

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/ml300280g
Kuduk, Scott D; Chang, Ronald K; Greshock, Thomas J; Ray, William J; Ma, Lei; Wittmann, Marion; Seager, Matthew A; Koeplinger, Kenneth A; Thompson, Charles D; Hartman, George D; Bilodeau, Mark T
发表日期：2012
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Quinolizidinone carboxylic acids as CNS penetrant, selective m1 allosteric muscarinic receptor modulators

喹诺里酮羧酸作为中枢神经系统穿透性选择性m1变构毒蕈碱受体调节剂

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/ml100095k
Kuduk, Scott D; Chang, Ronald K; Di Marco, Christina N; Ray, William J; Ma, Lei; Wittmann, Marion; Seager, Matthew A; Koeplinger, Kenneth A; Thompson, Charles D; Hartman, George D; Bilodeau, Mark T
信号转导
神经科学
发表日期：2010
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