The inositol pyrophosphate 5-InsP(7) drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α.
肌醇焦磷酸 5-InsP(7) 通过解除 PI3K p85α 的自身抑制结构域来驱动钠钾泵降解
期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.abb8542
Chin Alfred C, Gao Zhe, Riley Andrew M, Furkert David, Wittwer Christopher, Dutta Amit, Rojas Tomas, Semenza Evan R, Felder Robin A, Pluznick Jennifer L, Jessen Henning J, Fiedler Dorothea, Potter Barry V L, Snyder Solomon H, Fu Chenglai
