文献库，生知库 | 链接生命科学的每一步

Yong-Hyun Han ，Emily J Onufer ，Li-Hao Huang ，Robert W Sprung ，W Sean Davidson ，Rafael S Czepielewski ，Mary Wohltmann ，Mary G Sorci-Thomas ，Brad W Warner ，Gwendalyn J Randolph

毒理研究

肝损伤

发表日期：2021

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Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling

VIA组PLA2（iPLA2β）在胰岛β细胞信号传导中位于p38丝裂原活化蛋白激酶（MAPK）的上游被激活。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M111.285114

Song, Haowei; Wohltmann, Mary; Tan, Min; Bao, Shunzhong; Ladenson, Jack H; Turk, John

Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents

VIB组磷脂酶A2促进INS-1胰岛瘤细胞增殖，并减弱炎症细胞因子和氧化剂诱导的脂质过氧化和细胞凋亡。

期刊:Oxidative Medicine and Cellular Longevity

影响因子:

doi:10.1155/2012/989372

Bao, Shunzhong; Song, Haowei; Tan, Min; Wohltmann, Mary; Ladenson, Jack H; Turk, John

Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA(2)Î² (VIA)-deficient mice.

成像显示 iPLA(2)β (VIA) 缺陷小鼠脑内二十二碳六烯酸代谢和信号传导降低

期刊:Journal of Lipid Research

影响因子:4.1

doi:10.1194/jlr.M008334

Basselin Mireille, Rosa Angelo O, Ramadan Epolia, Cheon Yewon, Chang Lisa, Chen Mei, Greenstein Deanna, Wohltmann Mary, Turk John, Rapoport Stanley I

代谢

发表日期：2010

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Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations

PLA2G6 突变引起的婴儿神经轴突营养不良小鼠模型中膜稳态紊乱和泛素化蛋白积累

期刊:American Journal of Pathology

影响因子:3.6

doi:10.2353/ajpath.2008.070823

Malik, Ibrahim; Turk, John; Mancuso, David J; Montier, Laura; Wohltmann, Mary; Wozniak, David F; Schmidt, Robert E; Gross, Richard W; Kotzbauer, Paul T

Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice

VIA组磷脂酶A2（iPLA2β）基因敲除小鼠的骨骼形态年龄相关变化加速。

期刊:American Journal of Pathology

影响因子:3.6

doi:10.2353/ajpath.2008.070756

Ramanadham, Sasanka; Yarasheski, Kevin E; Silva, Matthew J; Wohltmann, Mary; Novack, Deborah Veis; Christiansen, Blaine; Tu, Xiaolin; Zhang, Sheng; Lei, Xiaoyong; Turk, John

发表日期：2008

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Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice

在胰岛β细胞中过表达iPLA2β的小鼠和iPLA2β敲除小鼠中，葡萄糖稳态、胰岛素分泌和胰岛磷脂的变化

期刊:American Journal of Physiology-Endocrinology and Metabolism

影响因子:3.1

doi:10.1152/ajpendo.00474.2007

Bao, Shunzhong; Jacobson, David A; Wohltmann, Mary; Bohrer, Alan; Jin, Wu; Philipson, Louis H; Turk, John

Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility

不表达VIA组磷脂酶A2的雄性小鼠产生的精子活力受损，生育能力大大降低。

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M406489200

Bao, Shunzhong; Miller, David J; Ma, Zhongmin; Wohltmann, Mary; Eng, Grace; Ramanadham, Sasanka; Moley, Kelle; Turk, John

发表日期：2004

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Enterically derived high-density lipoprotein restrains liver injury through the portal vein

肠源性高密度脂蛋白通过门静脉抑制肝损伤

Group VIA PLA2 (iPLA2β) is activated upstream of p38 mitogen-activated protein kinase (MAPK) in pancreatic islet β-cell signaling

VIA组PLA2（iPLA2β）在胰岛β细胞信号传导中位于p38丝裂原活化蛋白激酶（MAPK）的上游被激活。

Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents

VIB组磷脂酶A2促进INS-1胰岛瘤细胞增殖，并减弱炎症细胞因子和氧化剂诱导的脂质过氧化和细胞凋亡。

Imaging decreased brain docosahexaenoic acid metabolism and signaling in iPLA(2)Î² (VIA)-deficient mice.

成像显示 iPLA(2)β (VIA) 缺陷小鼠脑内二十二碳六烯酸代谢和信号传导降低

Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations

PLA2G6 突变引起的婴儿神经轴突营养不良小鼠模型中膜稳态紊乱和泛素化蛋白积累

Age-related changes in bone morphology are accelerated in group VIA phospholipase A2 (iPLA2beta)-null mice

VIA组磷脂酶A2（iPLA2β）基因敲除小鼠的骨骼形态年龄相关变化加速。

Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress iPLA2beta in pancreatic beta-cells and in iPLA2beta-null mice

在胰岛β细胞中过表达iPLA2β的小鼠和iPLA2β敲除小鼠中，葡萄糖稳态、胰岛素分泌和胰岛磷脂的变化

Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility

不表达VIA组磷脂酶A2的雄性小鼠产生的精子活力受损，生育能力大大降低。