日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting the epithelium in pulmonary fibrosis

靶向肺纤维化中的上皮细胞

Lizé, Muriel; Mayr, Christoph H; Bleck, Marina; Wollin, Lutz; Wohnhaas, Christian T; Shalashova, Irina; Olbrich, Heiko; Heilker, Ralf; Engler, Anna; Bammert, Marie-Therese; Schlüter, Holger; Geillinger-Kästle, Kerstin; Soetopo, Devona; Klee, Stephan; Wolf, Felix; Gokey, Jason J; Stahl, Heiko; Klimowicz, Alexander C; McCall, A Scott; Kropski, Jonathan A; Blackwell, Timothy S; Thomas, Matthew J

Avenciguat: a novel soluble guanylate cyclase activator that affects multiple cell types to inhibit IFN-1 signalling and fibrosis

阿文西呱:一种新型可溶性鸟苷酸环化酶激活剂,可影响多种细胞类型,抑制IFN-1信号传导和纤维化。

Kaufman, Julia; Nabozny, Gerald; Tran-Manh, Cuong; Liebel, Christoph; Zhou, Xiang; Daley, Lee-Anne; Wang, Chao-Ting; Ebenezer, David L; Delic, Denis; Wohnhaas, Christian T; Trinh-Minh, Thuong; Distler, Jörg H W

Monocyte-derived alveolar macrophages are key drivers of smoke-induced lung inflammation and tissue remodeling

单核细胞衍生的肺泡巨噬细胞是吸烟引起的肺部炎症和组织重塑的关键驱动因素

Christian T Wohnhaas, Kevin Baßler, Carolin K Watson, Yang Shen, Germán G Leparc, Cornelia Tilp, Fabian Heinemann, David Kind, Birgit Stierstorfer, Denis Delić, Thomas Brunner, Florian Gantner, Joachim L Schultze, Coralie Viollet, Patrick Baum

Single-cell analysis implicates TH17-to-TH2 cell plasticity in the pathogenesis of palmoplantar pustulosis

单细胞分析表明 TH17 至 TH2 细胞的可塑性与掌跖脓疱病的发病机制有关

Daniel McCluskey, Natashia Benzian-Olsson, Satveer K Mahil, Niina Karoliina Hassi, Christian T Wohnhaas; APRICOT and PLUM study team; A David Burden, Christopher E M Griffiths, John R Ingram, Nick J Levell, Richard Parslew, Andrew E Pink, Nick J Reynolds, Richard B Warren, Sudha Visvanathan, Patrick

IL36 is a critical upstream amplifier of neutrophilic lung inflammation in mice

IL36 是小鼠中性粒细胞肺部炎症的关键上游放大器

Carolin K Koss, Christian T Wohnhaas, Jonathan R Baker, Cornelia Tilp, Michèl Przibilla, Carmen Lerner, Silvia Frey, Martina Keck, Cara M M Williams, Daniel Peter, Meera Ramanujam, Jay Fine, Florian Gantner, Matthew Thomas, Peter J Barnes, Louise E Donnelly, Karim C El Kasmi

Cigarette Smoke Specifically Affects Small Airway Epithelial Cell Populations and Triggers the Expansion of Inflammatory and Squamous Differentiation Associated Basal Cells

香烟烟雾特别影响小气道上皮细胞群,并引发炎症和鳞状分化相关基底细胞的扩增

Christian T Wohnhaas, Julia A Gindele, Tobias Kiechle, Yang Shen, Germán G Leparc, Birgit Stierstorfer, Heiko Stahl, Florian Gantner, Coralie Viollet, Jürgen Schymeinsky, Patrick Baum

Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture

间歇性暴露于香烟烟雾会改变气液界面培养中原代小气道上皮细胞的分化

Julia A Gindele, Tobias Kiechle, Kerstin Benediktus, Gerald Birk, Michael Brendel, Fabian Heinemann, Christian T Wohnhaas, Michelle LeBlanc, Haijun Zhang, Yael Strulovici-Barel, Ronald G Crystal, Matthew J Thomas, Birgit Stierstorfer, Karsten Quast, Jürgen Schymeinsky

Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients

牛皮癣患者皮肤的综合 microRNA/mRNA 表达谱

Denis Delić, Kerstin Wolk, Ramona Schmid, Ogsen Gabrielyan, Demetrios Christou, Kathrin Rieber, Marcel Rolser, Ines Jakob, Franziska Wiech, Manuela Griesser, Christian Wohnhaas, Georgios Kokolakis, Ellen Witte-Händel, Patrick Baum, Robert Sabat

Fecal MicroRNAs Show Promise as Noninvasive Crohn's Disease Biomarkers

粪便微小RNA有望成为非侵入性克罗恩病生物标志物

Christian T Wohnhaas, Ramona Schmid, Marcel Rolser, Eric Kaaru, Dominik Langgartner, Kathrin Rieber, Benjamin Strobel, Claudia Eisele, Franziska Wiech, Ines Jakob, Florian Gantner, Ivona Herichova, Richard Vinisko, Wulf O Böcher, Sudha Visvanathan, Fei Shen, Mark Panzenbeck, Ernest Raymond, Stefan O

DMSO cryopreservation is the method of choice to preserve cells for droplet-based single-cell RNA sequencing

DMSO 冷冻保存是保存细胞进行基于液滴的单细胞 RNA 测序的首选方法

Christian T Wohnhaas, Germán G Leparc, Francesc Fernandez-Albert, David Kind, Florian Gantner, Coralie Viollet, Tobias Hildebrandt, Patrick Baum