日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Oral USC-093, a novel homoserinamide analogue of the tyrosinamide (S)-HPMPA prodrug USC-087 has decreased nephrotoxicity while maintaining antiviral efficacy against human adenovirus infection of Syrian hamsters

口服 USC-093 是一种新型的酪氨酰胺 (S)-HPMPA 前药 USC-087 的高丝氨酸酰胺类似物,在保持对叙利亚仓鼠人类腺病毒感染的抗病毒功效的同时,降低了肾毒性。

Tollefson, Ann E; Riemann, Samantha B; Ying, Baoling; Spencer, Jacqueline F; Overhulse, Justin M; Kashemirov, Boris A; Wold, William S M; McKenna, Charles E; Toth, Karoly

Filociclovir Is a Potent In Vitro and In Vivo Inhibitor of Human Adenoviruses

菲洛西洛韦是一种强效的体外和体内人类腺病毒抑制剂

Toth, Karoly; Hussein, Islam T M; Tollefson, Ann E; Ying, Baoling; Spencer, Jacqueline F; Eagar, Jessica; James, Scott H; Prichard, Mark N; Wold, William S M; Bowlin, Terry L

The Virology of Taterapox Virus In Vitro

体外塔特痘病毒的病毒学研究

Parker, Scott; Camilo de Oliveira, Leonardo; Lefkowitz, Elliot J; Hendrickson, Robert Curtis; Bonjardim, Cláudio A; Wold, William S M; Hartzler, Hollyce; Crump, Ryan; Buller, Robert Mark

Anti-adenoviral Artificial MicroRNAs Expressed from AAV9 Vectors Inhibit Human Adenovirus Infection in Immunosuppressed Syrian Hamsters.

由 AAV9 载体表达的抗腺病毒人工微RNA可抑制免疫抑制的叙利亚仓鼠体内的人类腺病毒感染

Schaar Katrin, Geisler Anja, Kraus Milena, Pinkert Sandra, Pryshliak Markian, Spencer Jacqueline F, Tollefson Ann E, Ying Baoling, Kurreck Jens, Wold William S, Klopfleisch Robert, Toth Karoly, Fechner Henry

Pathology in Permissive Syrian Hamsters after Infection with Species C Human Adenovirus (HAdV-C) Is the Result of Virus Replication: HAdV-C6 Replicates More and Causes More Pathology than HAdV-C5

易感叙利亚仓鼠感染C型人腺病毒(HAdV-C)后的病理变化是病毒复制的结果:HAdV-C6的复制量和引起的病理变化均高于HAdV-C5。

Tollefson, Ann E; Ying, Baoling; Spencer, Jacqueline F; Sagartz, John E; Wold, William S M; Toth, Karoly

Correction: STAT2 Knockout Syrian Hamsters Support Enhanced Replication and Pathogenicity of Human Adenovirus, Revealing an Important Role of Type I Interferon Response in Viral Control

更正:STAT2基因敲除的叙利亚仓鼠支持人腺病毒复制增强和致病性增强,揭示了I型干扰素反应在病毒控制中的重要作用

Toth, Karoly; Lee, Sang R; Ying, Baoling; Spencer, Jacqueline F; Tollefson, Ann E; Sagartz, John E; Kong, Il-Keun; Wang, Zhongde; Wold, William S M

BMET-26: PHASE 2 STUDY OF VB-111, AN ANTI-CANCER GENE THERAPY, AS MONOTHERAPY FOLLOWED BY COMBINATION OF VB-111 WITH BEVACIZUMAB, IN PATIENTS WITH RECURRENT GLIOBLASTOMA

BMET-26:VB-111(一种抗癌基因疗法)单药治疗后联合贝伐珠单抗治疗复发性胶质母细胞瘤患者的II期研究

Ying, Baoling; Toth, Karoly; Spencer, Jacqueline F; Aurora, Rajeev; Wold, William S M; Kato, Yuki; Scharnweber, Rudi; Inagaki, Akhito; Kamijima, Shuichi; Hickey, Michelle; Lisiero, Dominique; Hermann, Kip; Soto, Horacio; Antonios, Joe; Sedighim, Shaina; Okada, Hideho; Liau, Linda; Klatzmann, David; Prins, Robert; Kashara, Noriyuki; Brenner, Andrew; Cohen, Yael; Vredenburgh, James; Peters, Katherine; Nayak, Lakshmi; Blumenthal, Deborah; Bokstein, Felix; Breitbart, Eyal; Bangio, Livnat; Sher, Naamit; Harats, Dror; Wen, Patrick

Adenovirus vectors for gene therapy, vaccination and cancer gene therapy

用于基因治疗、疫苗接种和癌症基因治疗的腺病毒载体

Wold, William S M; Toth, Karoly

Increasing the efficacy of oncolytic adenovirus vectors

提高溶瘤腺病毒载体的疗效

Toth, Karoly; Wold, William S M

Pre-existing immunity and passive immunity to adenovirus 5 prevents toxicity caused by an oncolytic adenovirus vector in the Syrian hamster model

预先存在的免疫力和针对腺病毒5的被动免疫力可预防叙利亚仓鼠模型中溶瘤腺病毒载体引起的毒性。

Dhar, Debanjan; Spencer, Jacqueline F; Toth, Karoly; Wold, William S M