日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolic stress and early cell death in photoreceptor precursor cells following retinal transplantation

视网膜移植后感光细胞前体细胞的代谢应激和早期细胞死亡

Sudharsan, Raghavi; Dolgova, Natalia; Kwok, Jennifer; Gray, Alexa; Sato, Yu; Madrigal, Agustin Luz; Susaimanickam, Praveen Joseph; Kriukov, Emil; Baranov, Petr; Wolfe, John H; Aguirre, Gustavo D; Gamm, David M; Beltran, William A

Effect of disease progression on CSF-directed AAV gene therapy in a large brain animal model of lysosomal storage disease.

在溶酶体贮积症大型脑动物模型中,疾病进展对脑脊液靶向AAV基因治疗的影响

Hunter Jacqueline E, Molony Caitlyn M, Panek Wojciech K, Vite Charles H, Chawla Sanjeev, Poptani Harish, Wolfe John H

Intracisternal vs intraventricular injection of AAV1 result in comparable, widespread transduction of the dog brain

脑池内注射与脑室内注射AAV1可导致犬脑内相似的广泛转导。

Hunter, Jacqueline E; Vite, Charles H; Molony, Caitlyn M; O'Donnell, Patricia A; Wolfe, John H

Choroid plexus-targeted viral gene therapy for alpha-mannosidosis, a prototypical neurometabolic lysosomal storage disease

针对脉络丛的病毒基因疗法可用于治疗α-甘露糖苷贮积症,这是一种典型的神经代谢溶酶体贮积症。

Choi, Eun-Young; Wolfe, John H; Kaler, Stephen G

Systemic immunosuppression promotes survival and integration of subretinally implanted human ESC-derived photoreceptor precursors in dogs

全身免疫抑制可促进犬视网膜下植入的人类胚胎干细胞衍生的光感受器前体细胞的存活和整合。

Ripolles-Garcia, Ana; Dolgova, Natalia; Phillips, M Joseph; Savina, Svetlana; Ludwig, Allison L; Stuedemann, Sara A; Nlebedum, Uchenna; Wolfe, John H; Garden, Oliver A; Maminishkis, Arvydas; Amaral, Juan; Bharti, Kapil; Gamm, David M; Aguirre, Gustavo D; Beltran, William A

Islet1 Precursors Contribute to Mature Interneuron Subtypes in Mouse Neocortex

Islet1前体细胞参与小鼠新皮层成熟中间神经元亚型的形成

Siddiqi, Faez; Trakimas, Alexandria L; Joseph, Donald J; Lippincott, Margaret L; Marsh, Eric D; Wolfe, John H

In Situ Hybridization for Detection of AAV-Mediated Gene Expression

原位杂交检测AAV介导的基因表达

Hunter, Jacqueline E; Gurda, Brittney L; Yoon, Sea Young; Castle, Michael J; Wolfe, John H

Malformation of the Posterior Cerebellar Vermis Is a Common Neuroanatomical Phenotype of Genetically Engineered Mice on the C57BL/6 Background

后小脑蚓部畸形是C57BL/6背景下基因工程小鼠常见的神经解剖学表型

Cuoco, Joshua A; Esposito, Anthony W; Moriarty, Shannon; Tang, Ying; Seth, Sonika; Toia, Alyssa R; Kampton, Elias B; Mayr, Yevgeniy; Khan, Mussarah; Khan, Mohammad B; Mullen, Brian R; Ackman, James B; Siddiqi, Faez; Wolfe, John H; Savinova, Olga V; Ramos, Raddy L

Clinical Improvement of Alpha-mannosidosis Cat Following a Single Cisterna Magna Infusion of AAV1

单次经枕大池输注AAV1后,α-甘露糖苷酶缺乏症猫的临床症状得到改善

Yoon, Sea Young; Bagel, Jessica H; O'Donnell, Patricia A; Vite, Charles H; Wolfe, John H

Stem Cell Therapy for the Central Nervous System in Lysosomal Storage Diseases

溶酶体贮积症中枢神经系统干细胞疗法

Siddiqi, Faez; Wolfe, John H