日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol

通过挖掘 LIPG 等位基因谱,揭示了罕见和常见调控变异对高密度脂蛋白胆固醇的贡献

Khetarpal, Sumeet A; Edmondson, Andrew C; Raghavan, Avanthi; Neeli, Hemanth; Jin, Weijun; Badellino, Karen O; Demissie, Serkalem; Manning, Alisa K; DerOhannessian, Stephanie L; Wolfe, Megan L; Cupples, L Adrienne; Li, Mingyao; Kathiresan, Sekar; Rader, Daniel J

Lipoprotein(a) is strongly associated with coronary artery calcification in type-2 diabetic women

脂蛋白(a)与2型糖尿病女性的冠状动脉钙化密切相关。

Qasim, Atif N; Martin, Seth S; Mehta, Nehal N; Wolfe, Megan L; Park, James; Schwartz, Stanley; Schutta, Mark; Iqbal, Nayyar; Reilly, Muredach P

Short-term treatment with high-dose atorvastatin reduces LDL cholesterol but shows no anti-inflammatory effects in normolipidemic subjects with normal CRP levels.

短期使用高剂量阿托伐他汀治疗可降低低密度脂蛋白胆固醇,但对血脂正常且 CRP 水平正常的受试者没有抗炎作用

Millar John S, Ky Bonnie, Wolfe Megan L, Pruscino Leticia, Baer Amanda, Rader Daniel J

Potent and selective PPAR-alpha agonist LY518674 upregulates both ApoA-I production and catabolism in human subjects with the metabolic syndrome

强效且选择性的PPAR-α激动剂LY518674可上调代谢综合征患者体内ApoA-I的生成和分解代谢。

Millar, John S; Duffy, Danielle; Gadi, Ramprasad; Bloedon, LeAnne T; Dunbar, Richard L; Wolfe, Megan L; Movva, Rajesh; Shah, Ashish; Fuki, Ilia V; McCoy, Mary; Harris, Cynthia J; Wang, Ming-Dauh; Howey, Daniel C; Rader, Daniel J

Atheroprotective lipoprotein effects of a niacin-simvastatin combination compared to low- and high-dose simvastatin monotherapy

烟酸-辛伐他汀联合用药与低剂量和高剂量辛伐他汀单药治疗相比,对动脉粥样硬化脂蛋白的影响

Airan-Javia, Subha L; Wolf, Ronald L; Wolfe, Megan L; Tadesse, Mahlet; Mohler, Emile; Reilly, Muredach P

Resistin gene variation is associated with systemic inflammation but not plasma adipokine levels, metabolic syndrome or coronary atherosclerosis in nondiabetic Caucasians.

在非糖尿病白种人中,抵抗素基因变异与全身炎症有关,但与血浆脂肪因子水平、代谢综合征或冠状动脉粥样硬化无关

Qasim Atif N, Metkus Thomas S, Tadesse Mahlet, Lehrke Michael, Restine Stephanie, Wolfe Megan L, Hannenhalli Sridhar, Cappola Thomas, Rader Daniel J, Reilly Muredach P

Adipokines, insulin resistance, and coronary artery calcification.

脂肪因子、胰岛素抵抗和冠状动脉钙化

Qasim Atif, Mehta Nehal N, Tadesse Mahlet G, Wolfe Megan L, Rhodes Thomas, Girman Cynthia, Reilly Muredach P

Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis

代谢综合征患者的内皮脂肪酶浓度升高,且与冠状动脉粥样硬化相关。

Badellino, Karen O; Wolfe, Megan L; Reilly, Muredach P; Rader, Daniel J

Associations among race/ethnicity, ApoC-III genotypes, and lipids in HIV-1-infected individuals on antiretroviral therapy

抗逆转录病毒治疗中 HIV-1 感染者的种族/民族、ApoC-III 基因型和血脂之间的关联

Foulkes, Andrea S; Wohl, David A; Frank, Ian; Puleo, Elaine; Restine, Stephanie; Wolfe, Megan L; Dube, Michael P; Tebas, Pablo; Reilly, Muredach P

Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion

胆固醇酯转移蛋白抑制对高密度脂蛋白亚型、载脂蛋白AI代谢和粪便甾醇排泄的影响

Brousseau, Margaret E; Diffenderfer, Margaret R; Millar, John S; Nartsupha, Chorthip; Asztalos, Bela F; Welty, Francine K; Wolfe, Megan L; Rudling, Mats; Björkhem, Ingemar; Angelin, Bo; Mancuso, James P; Digenio, Andres G; Rader, Daniel J; Schaefer, Ernst J