Activation-induced expression of CD137 permits detection, isolation, and expansion of the full repertoire of CD8+ T cells responding to antigen without requiring knowledge of epitope specificities.
CD137 的激活诱导表达使得无需了解表位特异性即可检测、分离和扩增对特定抗原有反应的 CD8+ T 细胞的全部库
期刊:Blood
影响因子:23.1
doi:10.1182/blood-2006-11-056168
Wolfl Matthias, Kuball Jürgen, Ho William Y, Nguyen Hieu, Manley Thomas J, Bleakley Marie, Greenberg Philip D