Rapid-Turnaround Co-Administration of mRNA-Based MHC-I and MHC-II-Restricted Neoantigens Enhances Immune Responses of Antigen-Specific CD8(+) T Cells and Anti-Cancer Efficacy in Colorectal Cancer.
快速联合应用基于 mRNA 的 MHC-I 和 MHC-II 限制性新抗原可增强抗原特异性 CD8(+) T 细胞的免疫反应和结直肠癌的抗癌疗效。
期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202506426
Cho Seongje, Kwak Woori, Yoon Hyunho, Lee Jisun, Lee Seonghyun, Park Hyo-Jung, Jo Sohee, Lee Yu-Sun, Seo Yu-Jeong, Cho Youngran, Bae Seo-Hyeon, Yoon Subin, Roh Gahyun, Ha Dahyeon, Oh Ayoung, Choi Eun-Jin, Lee Soo-Yeon, Choi Huijeong, Kim Jungmin, Lee Yeeun, Lee Sowon, Park Sang-In, Kim Dae-Keun, Chang Jun, Kim Ki Tae, Kim Kwoneel, Nam Jae-Hwan
肿瘤
肠癌
T细胞
肿瘤免疫
CD8
细胞生物学
免疫/内分泌
