日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

多发性骨髓瘤中EZH2的过度表达与预后不良和细胞周期调控失调相关。

Pawlyn, C; Bright, M D; Buros, A F; Stein, C K; Walters, Z; Aronson, L I; Mirabella, F; Jones, J R; Kaiser, M F; Walker, B A; Jackson, G H; Clarke, P A; Bergsagel, P L; Workman, P; Chesi, M; Morgan, G J; Davies, F E

Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η

快速抗抑郁药通过增加 14-3-3η 的蛋白质稳定性刺激 GABA(B) 受体与 GIRK/Kir3 通道脱钩

E R Workman, P C G Haddick, K Bush, G A Dilly, F Niere, B V Zemelman, K F Raab-Graham

Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance

个性化癌症治疗:分子诊断、预测性生物标志物和耐药性

Gonzalez de Castro, D; Clarke, P A; Al-Lazikani, B; Workman, P

Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors

I类和I/IV类双重磷脂酰肌醇3-激酶(PI3K)抑制剂的临床前发现和临床开发进展

Shuttleworth, S J; Silva, F A; Cecil, A R L; Tomassi, C D; Hill, T J; Raynaud, F I; Clarke, P A; Workman, P

Guidelines for the welfare and use of animals in cancer research

癌症研究中动物福利和使用指南

Workman, P; Aboagye, E O; Balkwill, F; Balmain, A; Bruder, G; Chaplin, D J; Double, J A; Everitt, J; Farningham, D A H; Glennie, M J; Kelland, L R; Robinson, V; Stratford, I J; Tozer, G M; Watson, S; Wedge, S R; Eccles, S A

A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end points.

一项针对实体瘤的血管生成抑制剂 SU5416(semaxanib)的 I 期研究,纳入了动态对比 MR 药效学终点

O'Donnell A, Padhani A, Hayes C, Kakkar A J, Leach M, Trigo J M, Scurr M, Raynaud F, Phillips S, Aherne W, Hardcastle A, Workman P, Hannah A, Judson I

In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography

利用正电子发射断层扫描技术对[18F]氟乙硝唑作为肿瘤乏氧成像新标志物进行体内评估

Barthel, H; Wilson, H; Collingridge, D R; Brown, G; Osman, S; Luthra, S K; Brady, F; Workman, P; Price, P M; Aboagye, E O

Measuring changes in human tumour vasculature in response to therapy using functional imaging techniques

利用功能成像技术测量人类肿瘤血管系统对治疗的反应变化

Anderson, H; Price, P; Blomley, M; Leach, M O; Workman, P

The relationship between tumour oxygenation determined by oxygen electrode measurements and magnetic resonance spectroscopy of the fluorinated 2-nitroimidazole SR-4554

通过氧电极测量和氟化 2-硝基咪唑 SR-4554 的磁共振波谱法测定的肿瘤氧合之间的关系

Aboagye, E O; Maxwell, R J; Horsman, M R; Lewis, A D; Workman, P; Tracy, M; Griffiths, J R

Growth arrest vs direct cytotoxicity and the importance of molecular structure for the in vitro anti-tumour activity of ether lipids

生长抑制与直接细胞毒性以及分子结构对醚脂体外抗肿瘤活性的重要性

Lohmeyer, M; Workman, P