日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Overall Survival With First-Line vs Second-Line CDK4/6 Inhibitor Use in Advanced Breast Cancer: A Randomized Clinical Trial

晚期乳腺癌一线与二线 CDK4/6 抑制剂治疗的总生存期:一项随机临床试验

Wortelboer, Noor; van Ommen-Nijhof, Annemiek; Konings, Inge R; van der Noort, Vincent; van den Pol, Esther; Guerrero Páez, Cristina; Bakker, Sandra D; Hovenga, Sjoerd; Imholz, Alex L T; Kamm, Yvonne J L; van Leeuwen, Lobke; Luykx-de Bakker, Sylvia A; Mandigers, Caroline M P W; van Riel, Johanna M G H; Tol, Jolien; van de Wouw, Agnes J; Wilting, Saskia M; van Leeuwen-Stok, A Elise; Jager, Agnes; Sonke, Gabe S

Autologous fecal microbiota capsules are safe and potentially preserve beta-cell function in individuals with type 1 diabetes

自体粪便微生物胶囊安全有效,并有可能保护1型糖尿病患者的β细胞功能。

de Groen, Pleun; Fuhri Snethlage, Coco M; Wortelboer, Koen; Tokgöz, Sevilay; Davids, Mark; Verdoes, Xanthe; Westerbeke, Florine H M; Meijer, Rick I; Gotthardt, Martin; de Vos, Willem M; Herrema, Hilde; Nieuwdorp, Max; Hanssen, Nordin M J

Palbociclib exposure in relation to efficacy and toxicity in patients with advanced breast cancer

帕博西尼暴露量与晚期乳腺癌患者的疗效和毒性关系

Buijs, S M; Mohmaed Ali, M I; Oomen-de Hoop, E; Braal, C L; Wortelboer, N; van Ommen-Nijhof, A; Sonke, G S; Konings, I R; Jager, A; Steeghs, N; Siebinga, H; Mathijssen, R H J; Huitema, A D R; Koolen, S L W

Vinculin Y822 phosphorylation regulates adhesion remodeling during cardiomyocyte maturation.

Vinculin Y822 磷酸化调节心肌细胞成熟过程中的粘附重塑。

Li Xiaofei, Wortelboer Rainy, Song Yi, Balasubramanian Sahana, McLain Callie, Hernandez Manriquez Alex, Suh Joseph D, Hoffman Brenton D, Kwiatkowski Adam V, Radice Glenn L

Vinculin Y822 phosphorylation regulates adhesion remodeling during cardiomyocyte maturation

黏着斑蛋白Y822磷酸化调节心肌细胞成熟过程中的黏附重塑

Xiaofei Li,Rainy Wortelboer,Yi Song,Sahana Balasubramanian,Callie McLain,Alex Hernandez Manriquez,Joseph D Suh,Brenton D Hoffman,Adam V Kwiatkowski,Glenn L Radice

Randomised double-blind placebo-controlled trial protocol to evaluate the therapeutic efficacy of lyophilised faecal microbiota capsules amended with next-generation beneficial bacteria in individuals with metabolic dysfunction-associated steatohepatitis

一项随机双盲安慰剂对照试验方案,旨在评估添加新一代有益菌的冻干粪便微生物胶囊对代谢功能障碍相关脂肪性肝炎患者的治疗效果。

Augustijn, Quinten J J; Grefhorst, Aldo; de Groen, Pleun; Wortelboer, Koen; Seegers, Jos F Ml; Gül, Ismail Sahin; Suenaert, Peter; Verheij, Joanne; de Vos, Willem M; Herrema, Hilde; Nieuwdorp, Max; Holleboom, Adriaan G

Bacteriophages from treatment-naïve type 2 diabetes individuals drive an inflammatory response in human co-cultures of dendritic cells and T cells

未经治疗的 2 型糖尿病患者的噬菌体在人类树突状细胞和 T 细胞共培养中引发炎症反应

Torsten P M Scheithauer, Koen Wortelboer, Maaike Winkelmeijer, Xanthe Verdoes, Ömrüm Aydin, Yair I Z Acherman, Maurits L de Brauw, Max Nieuwdorp, Elena Rampanelli, Patrick A de Jonge, Hilde Herrema

Bacteriophages from treatment-naïve type 2 diabetes individuals drive an inflammatory response in human co-cultures of dendritic cells and T cells

来自未经治疗的 2 型糖尿病患者的噬菌体可诱导人树突状细胞和 T 细胞共培养物中的炎症反应。

Torsten P M Scheithauer,Koen Wortelboer ,Maaike Winkelmeijer,Xanthe Verdoes,Ömrüm Aydin ,Yair I Z Acherman,Maurits L de Brauw,Max Nieuwdorp,Elena Rampanelli ,Patrick A de Jonge ,Hilde Herrema

Oral histidine affects gut microbiota and MAIT cells improving glycemic control in type 2 diabetes patients

口服组氨酸可影响肠道菌群和MAIT细胞,从而改善2型糖尿病患者的血糖控制。

Warmbrunn, Moritz V; Attaye, Ilias; Aron-Wisnewsky, Judith; Rampanelli, Elena; van der Vossen, Eduard W J; Hao, Youling; Koopen, Annefleur; Bergh, Per-Olof; Stols-Gonçalves, Daniela; Mohamed, Nadia; Kemper, Marleen; Verdoes, Xanthe; Wortelboer, Koen; Davids, Mark; Belda, Eugeni; André, Sébastien; Hazen, Stanley; Clement, Karine; Groen, Bert; van Raalte, Daniel H; Herrema, Hilde; Backhed, Fredrik; Nieuwdorp, Max

Disentangle beneficial effects of strain engraftment after fecal microbiota transplantation in subjects with MetSyn

阐明粪便微生物移植后菌株植入对代谢综合征患者的有益作用

van der Vossen, Eduard W J; Davids, Mark; Voermans, Bas; Wortelboer, Koen; Hartstra, Annick V; Koopen, Annefleur M; de Groot, Pieter; Levin, Evgeni; Nieuwdorp, Max