Targeting DNA topoisomerases or checkpoint kinases results in an overload of chaperone systems, triggering aggregation of a metastable subproteome
靶向 DNA 拓扑异构酶或检查点激酶会导致分子伴侣系统超载，从而引发亚稳态亚蛋白质组的聚集
期刊:Elife
影响因子:6.4
doi:10.7554/eLife.70726
Wouter Huiting, Suzanne L Dekker #, Joris C J van der Lienden #, Rafaella Mergener, Maiara K Musskopf, Gabriel V Furtado, Emma Gerrits, David Coit, Mehrnoosh Oghbaie, Luciano H Di Stefano, Hein Schepers, Maria A W H van Waarde-Verhagen, Suzanne Couzijn, Lara Barazzuol, John LaCava, Harm H Kampinga,
