日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Inhibitory Receptor Siglec-8 Interacts With FcεRI and Globally Inhibits Intracellular Signaling in Primary Mast Cells Upon Activation

抑制性受体 Siglec-8 与 FcεRI 相互作用,并在激活后全面抑制原代肥大细胞中的细胞内信号传导

Wouter Korver, Alan Wong, Simon Gebremeskel, Gian Luca Negri, Julia Schanin, Katherine Chang, John Leung, Zachary Benet, Thuy Luu, Emily C Brock, Kenneth Luehrsen, Alan Xu, Bradford A Youngblood

Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells

发现一种能抑制和减少人类肥大细胞的Siglec-6激动性抗体

Julia Schanin,Wouter Korver,Emily C Brock,John Leung,Zachary Benet,Thuy Luu,Katherine Chang,Alan Xu,Naomi De Freitas,Kenneth Luehrsen,Michael A Brehm,Alan Wong,Bradford A Youngblood

Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells

Siglec-6 对人类肥大细胞的功能和表型表征

Piper A Robida, Clayton H Rische, Netali Ben-Baruch Morgenstern, Rethavathi Janarthanam, Yun Cao, Rebecca A Krier-Burris, Wouter Korver, Alan Xu, Thuy Luu, Julia Schanin, John Leung, Marc E Rothenberg, Joshua B Wechsler, Bradford A Youngblood, Bruce S Bochner, Jeremy A O'Sullivan

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody

肥大细胞和嗜酸性粒细胞活化与 COVID-19 和 TLR 介导的病毒性炎症有关:抗 Siglec-8 抗体的启示

Simon Gebremeskel, Julia Schanin, Krysta M Coyle, Melina Butuci, Thuy Luu, Emily C Brock, Alan Xu, Alan Wong, John Leung, Wouter Korver, Ryan D Morin, Robert P Schleimer, Bruce S Bochner, Bradford A Youngblood

IRAK4 kinase activity controls Toll-like receptor-induced inflammation through the transcription factor IRF5 in primary human monocytes

IRAK4 激酶活性通过转录因子 IRF5 控制原代人类单核细胞中 Toll 样受体诱导的炎症

Leah Cushing, Aaron Winkler, Scott A Jelinsky, Katherine Lee, Wouter Korver, Rachael Hawtin, Vikram R Rao, Margaret Fleming, Lih-Ling Lin

Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia

以 C 型凝集素样分子-1 为靶点进行急性髓系白血病抗体介导免疫治疗

Xiaoxian Zhao, Shweta Singh, Cecile Pardoux, Jingsong Zhao, Eric D Hsi, Arie Abo, Wouter Korver

The first propeller domain of LRP6 regulates sensitivity to DKK1

LRP6 的第一个螺旋桨结构域调节对 DKK1 的敏感性

Minke E Binnerts, Nenad Tomasevic, Jessica M Bright, John Leung, Victoria E Ahn, Kyung-Ah Kim, Xiaoming Zhan, Shouchun Liu, Shirlee Yonkovich, Jason Williams, Mei Zhou, Delphine Gros, Melissa Dixon, Wouter Korver, William I Weis, Arie Abo

R-Spondin family members regulate the Wnt pathway by a common mechanism

R-Spondin 家族成员通过共同的机制调节 Wnt 通路

Kyung-Ah Kim, Marie Wagle, Karolyn Tran, Xiaoming Zhan, Melissa A Dixon, Shouchun Liu, Delphine Gros, Wouter Korver, Shirlee Yonkovich, Nenad Tomasevic, Minke Binnerts, Arie Abo