Mechanistic Characterization of the Potency of THIOMAB Antibody-Drug Conjugates Targeting Staphylococcus aureus and ETbR-Expressing Tumor Cells Using Quantitative LC-MS/MS Analysis of Intracellular Drug Accumulation
利用定量LC-MS/MS分析细胞内药物积累,对靶向金黄色葡萄球菌和ETbR表达肿瘤细胞的THIOMAB抗体-药物偶联物的效力进行机制表征
期刊:Bioconjugate Chemistry
影响因子:3.9
doi:10.1021/acs.bioconjchem.4c00533
Hernandez-Barry, Hilda; Dela Cruz-Chuh, Josefa; Kajihara, Kimberly K; Asundi, Jyoti; Vandlen, Richard; Zhang, Donglu; Hazenbos, Wouter L W; Pillow, Thomas; Liu, Yichin; Wu, Cong; Kozak, Katherine R; Loyet, Kelly M