日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A nucleotide-independent, pan-RAS-targeted DARPin elicits anti-tumor activity in a multimodal manner

不依赖核苷酸、靶向泛RAS的DARPin以多模式方式发挥抗肿瘤活性。

Kapp, Jonas N; Verdurmen, Wouter P R; Schaefer, Jonas V; Kopra, Kari; Nagy-Davidescu, Gabriela; Richard, Elodie; Nokin, Marie-Julie; Ernst, Patrick; Tamaskovic, Rastislav; Schwill, Martin; Degen, Ralph; Scholl, Claudia; Santamaria, David; Plückthun, Andreas

Etiologies of endometriosis and model systems: is there a risk of a tunnel vision?

子宫内膜异位症的病因和模型系统:是否存在视野狭窄的风险?

Manavalan, Mary Ann; Babtain, Mona; Weessies, Myrthe; Nap, Annemiek; Verdurmen, Wouter P R; Taurin, Sebastien; Sater, Mai; Brock, Roland

Artificial intelligence-based tissue segmentation and cell identification in multiplex-stained histological endometriosis sections

基于人工智能的组织分割和细胞识别在多重染色组织学子宫内膜异位症切片中的应用

Korman, Scott E; Vissers, Guus; Gorris, Mark A J; Verrijp, Kiek; Verdurmen, Wouter P R; Simons, Michiel; Taurin, Sebastien; Sater, Mai; Nap, Annemiek W; Brock, Roland

Potent and selective eradication of tumor cells by an EpCAM-targeted Ras-degrading enzyme

利用靶向EpCAM的Ras降解酶高效且选择性地清除肿瘤细胞

Palacio-Castañeda, Valentina; van de Crommert, Bas; Verploegen, Elke; Overeem, Mike; van Oostrum, Jenny; Verdurmen, Wouter P R

Co-Culture of Glomerular Endothelial Cells and Podocytes in a Custom-Designed Glomerulus-on-a-Chip Model Improves the Filtration Barrier Integrity and Affects the Glomerular Cell Phenotype

在定制设计的肾小球芯片模型中共培养肾小球内皮细胞和足细胞可改善滤过屏障的完整性并影响肾小球细胞表型

Daan C 't Hart, Dilemin Yildiz, Valentina Palacio-Castañeda, Lanhui Li, Burcu Gumuscu, Roland Brock, Wouter P R Verdurmen, Johan van der Vlag, Tom Nijenhuis

Generation of Protein-Phosphorodiamidate Morpholino Oligomer Conjugates for Efficient Cellular Delivery via Anthrax Protective Antigen

利用炭疽保护性抗原高效细胞递送的蛋白质-磷脂酰二胺吗啉代寡聚体缀合物的生成

Palacio-Castañeda, Valentina; Brock, Roland; Verdurmen, Wouter P R

Thermodynamic Stability Is a Strong Predictor for the Delivery of DARPins to the Cytosol via Anthrax Toxin

热力学稳定性是炭疽毒素介导的DARPins递送至胞质溶胶的强有力预测因子。

Becker, Lukas; Singh Badwal, Jasleen; Brandl, Fabian; Verdurmen, Wouter P R; Plückthun, Andreas

Mimicking the Biology of Engineered Protein and mRNA Nanoparticle Delivery Using a Versatile Microfluidic Platform

利用多功能微流体平台模拟工程蛋白质和 mRNA 纳米颗粒输送的生物学

Valentina Palacio-Castañeda, Rik Oude Egberink, Arbaaz Sait, Lea Andrée, Benedetta Maria Sala, Negar Hassani Besheli, Egbert Oosterwijk, Johan Nilvebrant, Sander C G Leeuwenburgh, Roland Brock, Wouter P R Verdurmen

A Hybrid In Silico and Tumor-on-a-Chip Approach to Model Targeted Protein Behavior in 3D Microenvironments

一种结合计算机模拟和芯片肿瘤模型的混合方法,用于模拟靶向蛋白在三维微环境中的行为

Palacio-Castañeda, Valentina; Dumas, Simon; Albrecht, Philipp; Wijgers, Thijmen J; Descroix, Stéphanie; Verdurmen, Wouter P R

Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery

重新设计炭疽毒素保护性抗原以改善受体特异性蛋白质的递送

Lukas Becker, Wouter P R Verdurmen, Andreas Plückthun