日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

IL-15: from discovery to FDA approval

IL-15:从发现到FDA批准

Li, Zihai; Wrangle, John; He, Kai; Sprent, Jonathan; Rubinstein, Mark P

Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway.

通过阻断IL-33/IL1RL1通路,双重靶向肿瘤细胞和免疫微环境

Fu Denggang, Jiang Hua, Long Alan, Harris Ella, Guo Hongfen, Capitano Maegan L, Wrangle John, Faust Joshua R, Gopalakrishnapillai Anilkumar, Pasupuleti Santhosh Kumar, Ramdas Baskar, Kapur Reuben, Barwe Sonali P, Cheung Nai-Kong V, Paczesny Sophie

County-Level Cervical Cancer Screening Coverage and Differences in Incidence and Mortality

县级宫颈癌筛查覆盖率及发病率和死亡率差异

Amboree, Trisha L; Montealegre, Jane R; Damgacioglu, Haluk; Orr, Brian; Wrangle, John; Sonawane, Kalyani; Deshmukh, Ashish A

Novel Collaborations Across Training Programs to Support Mentoring in Sex Differences Research

跨培训项目的新型合作,旨在支持性别差异研究领域的指导工作

McRae-Clark, Aimee L; Brady, Kathleen T; Lee-Chavarria, Diana; McGinty, Jacqueline F; Gray, Kevin M; Wrangle, John; Chimowitz, Marc

Association of age with survival in older patients with cutaneous melanoma treated with immune checkpoint inhibitors

年龄与接受免疫检查点抑制剂治疗的老年皮肤黑色素瘤患者的生存率之间的关系

Howell, Ashley V; Gebregziabher, Mulugeta; Thiers, Bruce H; Graboyes, Evan M; Paulos, Chrystal M; Wrangle, John M; Hunt, Kelly J; Wallace, Kristin

Comparative analysis of antibodies to SARS-CoV-2 between asymptomatic and convalescent patients.

无症状感染者和康复期患者体内SARS-CoV-2抗体的比较分析

Dwyer Connor J, Cloud Colleen A, Wang Cindy, Heidt Philip, Chakraborty Paramita, Duke Tara F, McGue Shannon, Jeffcoat Braxton, Dunne Jaclyn, Johnson Logan, Choi Seungho, Nahhas Georges J, Gandy Amy S, Babic Nikolina, Nolte Frederick S, Howe Philip, Ogretmen Besim, Gangaraju Vamsi K, Tomlinson Stephen, Madden Brian, Bridges Tracy, Flume Patrick A, Wrangle John, Rubinstein Mark P, Baliga Prabhakar K, Nadig Satish N, Mehrotra Shikhar

Immune checkpoint inhibitors retain effectiveness in older patients with cutaneous metastatic melanoma

免疫检查点抑制剂对老年皮肤转移性黑色素瘤患者仍然有效

Howell, Ashley V; Gebregziabher, Mulugeta; Thiers, Bruce H; Paulos, Chrystal M; Wrangle, John M; Hunt, Kelly J; Wallace, Kristin

SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors

SLC36A1-mTORC1信号驱动对CDK4/6抑制剂的获得性耐药性

Akihiro Yoshida, Yiwen Bu, Shuo Qie, John Wrangle, E Ramsay Camp, E Starr Hazard, Gary Hardiman, Renée de Leeuw, Karen E Knudsen, J Alan Diehl

ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial

ALT-803(一种 IL-15 超激动剂)与 nivolumab 联合用于治疗转移性非小细胞肺癌患者:一项非随机、开放标签、1b 期试验

John M Wrangle, Vamsidhar Velcheti, Manish R Patel, Elizabeth Garrett-Mayer, Elizabeth G Hill, James G Ravenel, Jeffrey S Miller, Mohammad Farhad, Kate Anderton, Kathryn Lindsey, Michele Taffaro-Neskey, Carol Sherman, Samantha Suriano, Marzena Swiderska-Syn, Amy Sion, Joni Harris, Andie R Edwards, J

Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8(+) T Cells.

增强淋巴细胞清除不足以替代外源性IL2或IL15疗法来增强过继转移的效应CD8(+) T细胞的疗效

Johnson C Bryce, May Bennett R, Riesenberg Brian P, Suriano Samantha, Mehrotra Shikhar, Garrett-Mayer Elizabeth, Salem Mohamed L, Jeng Emily K, Wong Hing C, Paulos Chrystal M, Wrangle John M, Cole David J, Rubinstein Mark P