FOXP3(+) regulatory T cells use heparanase to access IL-2 bound to ECM in inflamed tissues
FOXP3(+)调节性T细胞利用肝素酶获取炎症组织中与细胞外基质结合的IL-2。
期刊:
影响因子:
doi:10.1101/2023.02.26.529772
Martinez, Hunter A; Koliesnik, Ievgen; Kaber, Gernot; Reid, Jacqueline K; Nagy, Nadine; Barlow, Graham; Falk, Ben A; Medina, Carlos O; Hargil, Aviv; Vlodavsky, Israel; Li, Jin-Ping; Pérez-Cruz, Magdiel; Tang, Sai-Wen; Meyer, Everett H; Wrenshall, Lucile E; Lord, James D; Garcia, K Christopher; Palmer, Theo D; Steinman, Lawrence; Nepom, Gerald T; Wight, Thomas N; Bollyky, Paul L; Kuipers, Hedwich F
炎症
T细胞
炎症/感染
FOXP3
T细胞
IL-2
细胞生物学
免疫/内分泌
