日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Quantitative estimates of inter-individual variability for new approach methodologies-based systemic safety toolbox using a population-based human in vitro model

利用基于人群的人体体外模型,对基于新方法论的系统安全性工具箱进行个体间变异性的定量估计

Alshammari, Ibrahim; Ford, Lucie C; Tsai, Han-Hsuan D; Lin, Hsing-Chieh; Negi, Chander K; Dickey, Allison N; Wright, Fred A; Middleton, Alistair M; Baltazar, Maria T; Reynolds, Joe; Cable, Sophie; Punt, Ans; Chiu, Weihsueh A; Rusyn, Ivan

Aberrant astroglial Kir4.1 activation in the anterior cingulate cortex disrupts neuronal excitability and social behavior

前扣带皮层中异常的星形胶质细胞 Kir4.1 激活会破坏神经元兴奋性和社交行为。

Tryndyak, Volodymyr P; Willett, Rose A; Song, Zhuolin; Dreval, Kostiantyn; Hughes Hanks, Jennifer M; Avigan, Mark I; Wright, Fred A; Beland, Frederick A; Rusyn, Ivan; Pogribny, Igor P; Li, Zhengmao; Zhang, Yixuan; Chen, Yan; Zhang, Ying; Pan, Yunlong; Wang, Kerui; Li, Chen; Zhao, Xiangyu; Hu, Weikang; Luo, Yifan; Cheng, Jiawen; Zhang, Hongzhen; Fukunaga, Kohji; Xia, Yankai; Jiang, Jiandong; Liu, Xiuxiu; Han, Feng; Lu, Yingmei

An approach to uncover significant direct and mediated relationships in multi-dimensional new approach methods (NAMs) data: A case study of hazard evaluation of petroleum UVCBs

一种揭示多维新方法(NAMs)数据中显著直接和间接关系的方法:以石油UVCBs危害评估为例

Zhou, Yi-Hui; Gallins, Paul J; Rusyn, Ivan; Wright, Fred A

Exploring experiences of the regulatory toxicology system: system-level promoters and inhibitors of new approach methodologies

探索监管毒理学体系的经验:新方法论的系统级促进因素和抑制因素

Bearth, Angela; Kopainsky, Birgit; Jones, Lowenna B; Vist, Gunn E; Husøy, Trine; Svendsen, Camilla; Whaley, Paul; Hoffmann, Sebastian; Ames, Heather M; Solstad, Gisle; Bloch, Denise; Čavoški, Aleksandra; Chiu, Weihsueh A; Davenport, Miles; Davies, Holly G; Giusti, Arianna; Hartung, Thomas; Kwon, Seok; Osborne, Olivia J; Rooney, Andrew A; Rousselle, Christophe; Sass, Jennifer B; Wright, Fred A; Mathisen, Gro H

A systematic analysis of read-across adaptations in testing proposal evaluations by the European Chemicals Agency

欧洲化学品管理局对测试提案评估中交叉参照调整的系统分析

Roe, Hannah M; Tsai, Han-Hsaun D; Ball, Nicholas; Wright, Fred A; Chiu, Weihsueh A; Rusyn, Ivan

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits

遗传因素对染色质可及性的影响揭示了肝脏基因调控和数量性状的机制

Currin, Kevin W; Perrin, Hannah J; Pandey, Gautam K; Alkhawaja, Abdalla A; Vadlamudi, Swarooparani; Musser, Annie E; Etheridge, Amy S; Broadaway, K Alaine; Rosen, Jonathan D; Varshney, Arushi; Chaudhry, Amarjit S; Gallins, Paul J; Wright, Fred A; Zhou, Yi-Hui; Parker, Stephen C J; Raffield, Laura M; Schuetz, Erin G; Innocenti, Federico; Mohlke, Karen L

Strain and Sex Variability in Liver, Kidney and Lung Levels of DNA Adducts EB-GII and bis-N7G-BD Following Inhalation Exposure to 1,3-Butadiene in Collaborative Cross Mice

合作杂交小鼠吸入1,3-丁二烯后肝脏、肾脏和肺脏中DNA加合物EB-GII和bis-N7G-BD水平的品系和性别差异

Moran, Erik; Goodman, Samantha; Wright, Fred A; Evans, Richard; Tretyakova, Natalia Y; Rusyn, Ivan

Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model

在严重MASH样肝损伤小鼠模型中对分子表型进行中介分析

Song, Zhuolin; Tryndyak, Volodymyr P; Willett, Rose A; Pogribny, Igor P; Rusyn, Ivan; Wright, Fred A

A workflow for human health hazard evaluation using transcriptomic data and Key Characteristics-based gene sets

利用转录组数据和基于关键特征的基因集进行人类健康危害评估的工作流程

Tsai, Han-Hsuan D; Oware, King D; Wright, Fred A; Chiu, Weihsueh A; Rusyn, Ivan

HAP-SAMPLE2: data-based resampling for association studies with admixture

HAP-SAMPLE2:基于数据的混合关联研究重采样

Sun, George; Ting, Bryan W; Wright, Fred A; Zhou, Yi-Hui