日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Common and rare genetic variants show network convergence for a majority of human traits

常见和罕见的基因变异在大多数人类性状中都表现出网络趋同性。

Wright, Sarah N; Yang, Jane; Ideker, Trey

State of the interactomes: an evaluation of molecular networks for generating biological insights

相互作用组的状态:评估分子网络以产生生物学见解

Wright, Sarah N; Colton, Scott; Schaffer, Leah V; Pillich, Rudolf T; Churas, Christopher; Pratt, Dexter; Ideker, Trey

Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders.

对突触进行综合多组学表征,揭示了与神经发育障碍相关的 RNA 加工因子和泛素连接酶

Mei Yuan, Gosztyla Maya L, Tan Xinzhu, Dozier Lara E, Wilkinson Brent, McKetney Justin, Lee John, Chen Michael, Tsai Dorothy, Kopalle Hema, Gritsenko Marina A, Hartel Nicolas, Graham Nicholas A, Flores Ilse, Gilmore-Hall Stephen K, Xu Shuhao, Marquez Charlotte A, Liu Sophie N, Fong Dylan, Chen Jing, Licon Kate, Hong Derek, Wright Sarah N, Kreisberg Jason F, Nott Alexi, Smith Richard D, Qian Wei-Jun, Swaney Danielle L, Iakoucheva Lilia M, Krogan Nevan J, Patrick Gentry N, Zhou Yang, Feng Guoping, Coba Marcelo P, Yeo Gene W, Ideker Trey

Genome-wide association studies of human and rat BMI converge on synapse, epigenome, and hormone signaling networks

人类和鼠类BMI的全基因组关联研究结果均指向突触、表观基因组和激素信号网络。

Wright, Sarah N; Leger, Brittany S; Rosenthal, Sara Brin; Liu, Sophie N; Jia, Tongqiu; Chitre, Apurva S; Polesskaya, Oksana; Holl, Katie; Gao, Jianjun; Cheng, Riyan; Martinez, Angel Garcia; George, Anthony; Gileta, Alexander F; Han, Wenyan; Netzley, Alesa H; King, Christopher P; Lamparelli, Alexander; Martin, Connor; St Pierre, Celine L; Wang, Tengfei; Bimschleger, Hannah; Richards, Jerry; Ishiwari, Keita; Chen, Hao; Flagel, Shelly B; Meyer, Paul; Robinson, Terry E; Solberg Woods, Leah C; Kreisberg, Jason F; Ideker, Trey; Palmer, Abraham A

Common and rare genetic variants show network convergence for a majority of human traits

常见和罕见的基因变异在大多数人类性状中都表现出网络趋同性。

Wright, Sarah N; Yang, Jane; Ideker, Trey

Mapping the common gene networks that underlie related diseases

绘制相关疾病的共同基因网络

Rosenthal, Sara Brin; Wright, Sarah N; Liu, Sophie; Churas, Christopher; Chilin-Fuentes, Daisy; Chen, Chi-Hua; Fisch, Kathleen M; Pratt, Dexter; Kreisberg, Jason F; Ideker, Trey

A White-Box Machine Learning Approach for Revealing Antibiotic Mechanisms of Action.

一种用于揭示抗生素作用机制的白盒机器学习方法

Yang Jason H, Wright Sarah N, Hamblin Meagan, McCloskey Douglas, Alcantar Miguel A, Schrübbers Lars, Lopatkin Allison J, Satish Sangeeta, Nili Amir, Palsson Bernhard O, Walker Graham C, Collins James J