日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Inactivation of SARS-CoV-2 at acidic pH is driven by partial unfolding of spike.

SARS-CoV-2 在酸性 pH 值下的失活是由刺突蛋白的部分展开驱动的

Glas Irina, Zimmermann Liv, Luo Beiping, Pohl Marie O, Wrobel Antoni G, Schaub Aline, Klein Liviana K, David Shannon C, Gaggioli Elisabeth, Bluvshtein Nir, Huber Michael, Nenes Athanasios, Krieger Ulrich K, Peter Thomas, Kohn Tamar, Chlanda Petr, Stertz Silke

Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein

SARS-CoV-2刺突糖蛋白演化中的结构动力学

Calvaresi, Valeria; Wrobel, Antoni G; Toporowska, Joanna; Hammerschmid, Dietmar; Doores, Katie J; Bradshaw, Richard T; Parsons, Ricardo B; Benton, Donald J; Roustan, Chloë; Reading, Eamonn; Malim, Michael H; Gamblin, Steve J; Politis, Argyris

O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern

O-连接的唾液酸聚糖调节SARS-CoV-2刺突蛋白的蛋白水解,并可能导致相关变异株的突变轨迹。

Gonzalez-Rodriguez, Edgar; Zol-Hanlon, Mia; Bineva-Todd, Ganka; Marchesi, Andrea; Skehel, Mark; Mahoney, Keira E; Roustan, Chloë; Borg, Annabel; Di Vagno, Lucia; Kjær, Svend; Wrobel, Antoni G; Benton, Donald J; Nawrath, Philipp; Flitsch, Sabine L; Joshi, Dhira; González-Ramírez, Andrés Manuel; Wilkinson, Katalin A; Wilkinson, Robert J; Wall, Emma C; Hurtado-Guerrero, Ramón; Malaker, Stacy A; Schumann, Benjamin

Mechanism and evolution of human ACE2 binding by SARS-CoV-2 spike

SARS-CoV-2刺突蛋白与人ACE2结合的机制及演变

Wrobel, Antoni G

Heterologous humoral immunity to human and zoonotic coronaviruses: Aiming for the achilles heel

针对人类和人畜共患冠状病毒的异源体液免疫:直击要害

Ng, Kevin W; Faulkner, Nikhil; Wrobel, Antoni G; Gamblin, Steve J; Kassiotis, George

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

人类体内针对SARS-CoV-2的既有和新生体液免疫

Ng, Kevin W; Faulkner, Nikhil; Cornish, Georgina H; Rosa, Annachiara; Harvey, Ruth; Hussain, Saira; Ulferts, Rachel; Earl, Christopher; Wrobel, Antoni G; Benton, Donald J; Roustan, Chloe; Bolland, William; Thompson, Rachael; Agua-Doce, Ana; Hobson, Philip; Heaney, Judith; Rickman, Hannah; Paraskevopoulou, Stavroula; Houlihan, Catherine F; Thomson, Kirsty; Sanchez, Emilie; Shin, Gee Yen; Spyer, Moira J; Joshi, Dhira; O'Reilly, Nicola; Walker, Philip A; Kjaer, Svend; Riddell, Andrew; Moore, Catherine; Jebson, Bethany R; Wilkinson, Meredyth; Marshall, Lucy R; Rosser, Elizabeth C; Radziszewska, Anna; Peckham, Hannah; Ciurtin, Coziana; Wedderburn, Lucy R; Beale, Rupert; Swanton, Charles; Gandhi, Sonia; Stockinger, Brigitta; McCauley, John; Gamblin, Steve J; McCoy, Laura E; Cherepanov, Peter; Nastouli, Eleni; Kassiotis, George

Author Correction: SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects

作者更正:SARS-CoV-2 和蝙蝠 RaTG13 刺突糖蛋白的结构揭示了病毒进化和弗林蛋白酶切割效应。

Wrobel, Antoni G; Benton, Donald J; Xu, Pengqi; Roustan, Chloë; Martin, Stephen R; Rosenthal, Peter B; Skehel, John J; Gamblin, Steven J

Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation

通过 AP2 磷酸化调控内吞网格蛋白包被囊泡形成的时间顺序

Wrobel, Antoni G; Kadlecova, Zuzana; Kamenicky, Jan; Yang, Ji-Chun; Herrmann, Torsten; Kelly, Bernard T; McCoy, Airlie J; Evans, Philip R; Martin, Stephen; Müller, Stefan; Salomon, Susanne; Sroubek, Filip; Neuhaus, David; Höning, Stefan; Owen, David J

Ab initio solution of macromolecular crystal structures without direct methods

无需直接方法即可从头计算大分子晶体结构

McCoy, Airlie J; Oeffner, Robert D; Wrobel, Antoni G; Ojala, Juha R M; Tryggvason, Karl; Lohkamp, Bernhard; Read, Randy J

Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

瞬态Fcho1/2⋅Eps15/R⋅AP-2纳米簇启动AP-2网格蛋白适配器进行货物结合

Ma, Li; Umasankar, Perunthottathu K; Wrobel, Antoni G; Lymar, Anastasia; McCoy, Airlie J; Holkar, Sachin S; Jha, Anupma; Pradhan-Sundd, Tirthadipa; Watkins, Simon C; Owen, David J; Traub, Linton M