Wu Aimin相关文献与解析，生知库 | 链接生命科学的每一步

Bacteroides thetaiotaomicron: A symbiotic ally against diarrhea along with modulation of gut microbial ecological networks via tryptophan metabolism and AHR-Nrf2 signaling

拟杆菌属（Bacteroides thetaiotaomicron）：一种对抗腹泻的共生菌，同时通过色氨酸代谢和AHR-Nrf2信号通路调节肠道微生物生态网络

期刊:Journal of Advanced Research

影响因子:13

doi:10.1016/j.jare.2025.04.016

Luo, Yuheng; Lan, Cong; Ren, Wen; Wu, Aimin; Yu, Bing; He, Jun; Chen, Daiwen

Synergistic microenvironment therapy: a dual-function nanogel of supramolecular collagen ll-mimetic matrix and antioxidant MXene for attenuating intervertebral disc degeneration

协同微环境疗法：一种由超分子胶原蛋白II模拟基质和抗氧化剂MXene组成的双功能纳米凝胶，用于减轻椎间盘退变

期刊:Journal of Nanobiotechnology

影响因子:12.6

doi:10.1186/s12951-026-04211-w

Lyu, Gan; Gao, Zhan; Cao, Zhuoyi; Zhou, Qiwei; Chen, Yuli; Yang, Shu; Liang, Haibo; Lu, Xun; Li, Sunlong; Wang, Xinzhou; Sun, Shuai; Gao, Xiaoqing; Zhou, Yunlong; Wu, Aimin; Zhou, Xiaolin; Wang, Xiangyang

发表日期：2026

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A next-generation probiotic strain for gut health: Bacteroides cellulosilyticus LYH2 variant with anti-inflammatory and metabolic advantages

一种促进肠道健康的下一代益生菌菌株：具有抗炎和代谢优势的纤维素分解拟杆菌LYH2变种

期刊:EBioMedicine

影响因子:10.8

doi:10.1016/j.ebiom.2026.106232

Lan, Cong; Deng, Xiaofeng; Jin, Shen; Li, Hua; Liu, Yang; Wu, Aimin; Liu, Yanjiao; Zhang, Yifan; He, Jun; Dai, Zhaolai; Chen, Daiwen; Yu, Bing; Huang, Zhiqing; Mao, Xiangbing; Zheng, Ping; Yu, Jie; Luo, Junqiu; Yan, Hui; Luo, Yuheng

代谢

发表日期：2026

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Multifunctional Cu-doped Mn(3)O(4) nanozyme hydrogel microspheres for oral targeted treatment of inflammatory bowel disease

用于口服靶向治疗炎症性肠病的多功能铜掺杂Mn(3)O(4)纳米酶水凝胶微球

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2026.102932

Fan, Wei; Chen, Yinyin; Chen, Wenshuang; Gao, Zisong; Yang, Zhongke; Li, Hongyan; Wu, Aimin; Wang, Xianxiang

A bioinspired anisotropic anti-inflammatory scaffold enhances spinal nerve regeneration and neural circuit reconstruction via FGF13/Ca(2+)/CaMK2A/CREB pathway.

仿生各向异性抗炎支架通过 FGF13/Ca(2+)/CaMK2A/CREB 通路增强脊神经再生和神经回路重建。

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2026.102929

Jiang Minghao, Lu Wenjie, Zhuang Junyu, Song Jiahui, Zhao Yanfang, Zhou Cheng, Zhou Yangbo, Shu Weizhi, Zhu Zhongwei, Jiang Lelin, Wu Ping, Wu Aimin, Sheng Sunren, Zhu Sipin, Wang Zhouguang

MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.

利用压电微针递送经 MicroRNA-493-5p 工程改造的外泌体，对糖尿病伤口愈合中的巨噬细胞进行表观遗传调控。

期刊:Materials Today Bio

影响因子:10.2

doi:10.1016/j.mtbio.2026.102931

Chen Tao, Ouyang Lizhi, Mi Bobin, Sheng Yishen, Al-Smadi Fawwaz, Xu Hui, Wu Yaosen, Zhang Xiaolei, Zhou Kailiang, Wu Aimin, Wang Xiangyang, Liu Guohui, Zhang Wenqian

FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair.

FGF4 激活 FGFR1 - PI3K/AKT 信号通路，增强 Clec10a 介导的细胞内髓鞘碎片处理，促进脊髓修复。

期刊:Journal of Neuroinflammation

影响因子:10.1

doi:10.1186/s12974-026-03743-0

Lu Wenjie, Jiang Minghao, Zhuang Junyu, Song Jiahui, Zhou Cheng, Zhou Yangbo, Zhu Zhongwei, Wu Aimin, Sheng Sunren, Zhu Sipin, Wang Zhouguang

Causal neurodevelopmental origins of scoliosis: Multi-omics Mendelian randomization reveals brain-region-specific pathways and protein mediators

脊柱侧弯的神经发育因果起源：多组学孟德尔随机化揭示脑区特异性通路和蛋白质介质

期刊:Journal of Orthopaedic Translation

影响因子:7.8

doi:10.1016/j.jot.2025.09.010

Zhang, Shuhao; Lu, Sisi; Chen, Shiyu; Pan, Xiangxiang; Xia, Dongdong; Liu, Lue; Xie, Chenglong; Nisar, Majid; Wu, Aimin; Zhang, Xiaolei; Wang, Xiangyang; Huang, Chongan

Retinoic Acid Alleviates TGEV-Induced Ferroptosis by Activating the p62-NRF2-GPX4/HO-1 Pathway and Iron Metabolism in Intestinal Epithelial Cells.

视黄酸通过激活肠上皮细胞中的 p62-NRF2-GPX4/HO-1 通路和铁代谢来缓解 TGEV 诱导的铁死亡。

期刊:Nutrients

影响因子:5

doi:10.3390/nu18060994

Yin Conghui, Lai Xin, Pu Junning, Liu Chen, Luo Yuheng, He Jun, Yu Bing, Che Lianqiang, Wang Quyuan, Wang Huifen, Chen Daiwen, Wu Aimin

Universal scaling law: transcription factors homeostatically control promoter activity

普遍标度律：转录因子通过稳态控制启动子活性

Bacteroides thetaiotaomicron: A symbiotic ally against diarrhea along with modulation of gut microbial ecological networks via tryptophan metabolism and AHR-Nrf2 signaling

拟杆菌属（Bacteroides thetaiotaomicron）：一种对抗腹泻的共生菌，同时通过色氨酸代谢和AHR-Nrf2信号通路调节肠道微生物生态网络

Synergistic microenvironment therapy: a dual-function nanogel of supramolecular collagen ll-mimetic matrix and antioxidant MXene for attenuating intervertebral disc degeneration

协同微环境疗法：一种由超分子胶原蛋白II模拟基质和抗氧化剂MXene组成的双功能纳米凝胶，用于减轻椎间盘退变

A next-generation probiotic strain for gut health: Bacteroides cellulosilyticus LYH2 variant with anti-inflammatory and metabolic advantages

一种促进肠道健康的下一代益生菌菌株：具有抗炎和代谢优势的纤维素分解拟杆菌LYH2变种

Multifunctional Cu-doped Mn(3)O(4) nanozyme hydrogel microspheres for oral targeted treatment of inflammatory bowel disease

用于口服靶向治疗炎症性肠病的多功能铜掺杂Mn(3)O(4)纳米酶水凝胶微球

A bioinspired anisotropic anti-inflammatory scaffold enhances spinal nerve regeneration and neural circuit reconstruction via FGF13/Ca(2+)/CaMK2A/CREB pathway.

仿生各向异性抗炎支架通过 FGF13/Ca(2+)/CaMK2A/CREB 通路增强脊神经再生和神经回路重建。

MicroRNA-493-5p engineered exosomes delivered via piezoelectric microneedles for epigenetic modulation of macrophages in diabetic wound healing.

利用压电微针递送经 MicroRNA-493-5p 工程改造的外泌体，对糖尿病伤口愈合中的巨噬细胞进行表观遗传调控。

FGF4 activates FGFR1 - PI3K/AKT signaling to enhance Clec10a-mediated intracellular myelin debris processing and promote spinal cord repair.

FGF4 激活 FGFR1 - PI3K/AKT 信号通路，增强 Clec10a 介导的细胞内髓鞘碎片处理，促进脊髓修复。

Causal neurodevelopmental origins of scoliosis: Multi-omics Mendelian randomization reveals brain-region-specific pathways and protein mediators

脊柱侧弯的神经发育因果起源：多组学孟德尔随机化揭示脑区特异性通路和蛋白质介质

Retinoic Acid Alleviates TGEV-Induced Ferroptosis by Activating the p62-NRF2-GPX4/HO-1 Pathway and Iron Metabolism in Intestinal Epithelial Cells.

视黄酸通过激活肠上皮细胞中的 p62-NRF2-GPX4/HO-1 通路和铁代谢来缓解 TGEV 诱导的铁死亡。