日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.

通过针对 Galectin-3 的三重响应纳米颗粒进行病理定制的纳米疗法，可以实现针对主动脉夹层的多模式治疗。

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-025-04012-7
Lin Chi, Tsai Min-Lang, Chao Hsin-Yi, Cheng Tsai-Mu, Shih Chun-Ming, Wu Alexander T H, Cheng Chia-Hsiung, Hsiao Chen Yuan, Lu Hsin-Ying, Shih Chun-Che, Mi Fwu-Long
GALE
Galectin-3
发表日期：2026
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Integrated In Silico and Experimental Validation of Antrocin as a Plant-Derived Multi-Target Therapeutic for BRAF/MEK/PI3K-Driven Colorectal Cancer.

整合计算机模拟和实验验证安特罗辛作为植物来源的多靶点治疗药物对 BRAF/MEK/PI3K 驱动的结直肠癌的疗效。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26188780
Chen Jian-Syun, Enwolo-Chibueze Chioma Grace, Chinyama Harold Arnold, Lai Cheng-Ta, Ezeala Ifeyinwa Chioma, Huang Po-Yang, Wu Alexander T H, Huang Yan-Jiun
肠癌
肿瘤
BRAF
PI3K/Akt
发表日期：2025
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In Silico Identification of ANKRD22 as a Theragnostic Target for Pancreatic Cancer and Fostamatinib's Therapeutic Potential

计算机模拟鉴定ANKRD22为胰腺癌诊疗靶点及福斯他替尼的治疗潜力

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.105193
Huynh, Huong Thi Luu Kim; Lim, Hendrick Gao-Min; Lee, Yuan-Chii Gladys; Phan, Thien-Vy; Vo, Thanh-Hoa; Chen, Chien-Hsin; Wu, Alexander T H
胰腺癌
肿瘤
肿瘤免疫
发表日期：2025
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Nutraceutical Evaluation of Trigonelline's Therapeutic Potential by Targeting Bladder Cancer Stem Cells and Cancer-Associated Fibroblasts via Downregulation of TGFβ3/GLI2/YAP1 Signaling Hub.

通过下调 TGFβ3/GLI2/YAP1 信号枢纽靶向膀胱癌干细胞和癌相关成纤维细胞，评估葫芦巴碱的治疗潜力

期刊:International Journal of Medical Sciences
影响因子:3.2
doi:10.7150/ijms.107228
Kao Chien-Chang, Shih Jing-Wen, Huynh Huong Thi Luu Kim, Chang Ching-Hsin, Lawal Bashir, Iamsaard Sitthichai, Azizah Nur, Ritmaleni Ritmaleni, Lin Justin Kung-Yi, Huang Po-Yang, Wu Alexander T H, Liu Ming-Che
信号转导
发育与干细胞
细胞生物学
膀胱癌
肿瘤免疫
发表日期：2025
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Programmable MRI contrast switching for spatiotemporal mapping of thrombus maturation via enzyme-directed nanoprobe reconfiguration

利用酶导向纳米探针重构实现血栓成熟时空映射的可编程MRI对比度切换

期刊:Nano Convergence
影响因子:
doi:10.1186/s40580-025-00518-w
Lin, Chi; Hsu, Fang-Yu; Shih, Chun-Ming; Cheng, Tsai-Mu; Wu, Alexander T H; Cheng, Chia-Hsiung; Lu, Hsin-Ying; Shih, Chun-Che; Mi, Fwu-Long
心血管
发表日期：2025
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The intricate interplay between cancer stem cells and cell-of-origin of cancer: implications for therapeutic strategies

癌症干细胞与癌症起源细胞之间错综复杂的相互作用：对治疗策略的启示

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2024.1404628
Bamodu, Oluwaseun Adebayo; Chung, Chen-Chih; Pisanic, Thomas R 2nd; Wu, Alexander T H
肿瘤
肿瘤免疫
细胞生物学
干细胞
发育与干细胞
发表日期：2024
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Preclinical Evaluation of a Novel Small Molecule LCC-21 to Suppress Colorectal Cancer Malignancy by Inhibiting Angiogenic and Metastatic Signatures

新型小分子LCC-21抑制结直肠癌恶性肿瘤的临床前评价：通过抑制血管生成和转移特征

期刊:Cells
影响因子:5.2
doi:10.3390/cells12020266
Mokgautsi, Ntlotlang; Kuo, Yu-Cheng; Huang, Yan-Jiun; Chen, Chien-Hsin; Mukhopadhyay, Debabrata; Wu, Alexander T H; Huang, Hsu-Shan
肿瘤
肠癌
血管生成
肿瘤免疫
发表日期：2023
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Multi-Omics Identification of Genetic Alterations in Head and Neck Squamous Cell Carcinoma and Therapeutic Efficacy of HNC018 as a Novel Multi-Target Agent for c-MET/STAT3/AKT Signaling Axis

利用多组学方法鉴定头颈部鳞状细胞癌的基因改变，并评估新型多靶点药物 HNC018 对 c-MET/STAT3/AKT 信号通路的治疗效果

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms241210247
Khedkar, Harshita Nivrutti; Chen, Lung-Ching; Kuo, Yu-Cheng; Wu, Alexander T H; Huang, Hsu-Shan
肿瘤
MET
肿瘤免疫
JAK/STAT
信号转导
STAT3
细胞生物学
AKT
发表日期：2023
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Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent

CDK1、PBK 和 CHEK1 被鉴定为胶质母细胞瘤的致癌特征：利用生物信息学方法将达格列净重新用于治疗

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms242216396
Chinyama, Harold A; Wei, Li; Mokgautsi, Ntlotlang; Lawal, Bashir; Wu, Alexander T H; Huang, Hsu-Shan
CDK1
细胞生物学
肿瘤
肿瘤免疫
发表日期：2023
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In Silico Evaluation of HN-N07 Small Molecule as an Inhibitor of Angiogenesis and Lymphangiogenesis Oncogenic Signatures in Non-Small Cell Lung Cancer

利用计算机模拟评估小分子HN-N07作为非小细胞肺癌血管生成和淋巴管生成致癌特征抑制剂的活性

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines11072011
Chen, Lung-Ching; Mokgautsi, Ntlotlang; Kuo, Yu-Cheng; Wu, Alexander T H; Huang, Hsu-Shan
肺癌
肿瘤
肿瘤免疫
Angiogenesis
细胞生物学
血管生成
发表日期：2023
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