日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimization of synthetic human V(H) affinity and solubility through in vitro affinity maturation and minimal camelization.

通过体外亲和力成熟和最小驼峰化优化合成人V(H)的亲和力和溶解度

Bélanger Kasandra, Wu Cunle, Sulea Traian, van Faassen Henk, Callaghan Deborah, Aubry Annie, Sasseville Marc, Hussack Greg, Tanha Jamshid

Broadly reactive anti-VHH antibodies for characterizing, blocking, or activating nanobody-based CAR-T cells.

用于表征、阻断或激活基于纳米抗体的 CAR-T 细胞的广谱抗 VHH 抗体

McComb Scott, Dupont Bianca, Shepherd Alex, Bennychen Bigitha, Marcil Anne, Tamblyn Laura, Raphael Shalini, Sheff Joey, Hussack Greg, Moraitis Anna N, Wu Cunle, Aubry Annie, Gadoury Christine, Lippens Julie, Pagé Martine, Fortin Annie, Joubert Simon, Lamoureux Linda, Parat Marie, Plante Pierre, Malenfant Félix, Acchione Mauro, Pohankova Petra, Schrag Joe, Acel Andrea, Coutu Mathieu, Smith Emma, El Bakkouri Majida, Hill Jennifer J, Tremblay Tammy-Lynn, Manceur Aziza P, Faulkes Sharlene, Webb John, Zafer Ahmed, Zhu Qin, Nguyen Tina, Pon Robert A, Weeratna Risini D, Arbabi-Ghahroudi Mehdi

Polarization and cell-fate decision facilitated by the adaptor Ste50p in Saccharomyces cerevisiae

酿酒酵母中的接头蛋白Ste50p促进极化和细胞命运决定

Sharmeen, Nusrat; Law, Chris; Wu, Cunle

The adaptor protein Ste50 directly modulates yeast MAPK signaling specificity through differential connections of its RA domain

衔接蛋白Ste50通过其RA结构域的不同连接方式直接调节酵母MAPK信号传导的特异性。

Sharmeen, Nusrat; Sulea, Traian; Whiteway, Malcolm; Wu, Cunle

Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway

Ste50p的非典型RA结构域与未折叠的Opy2p胞质尾的结合对于高渗甘油途径至关重要。

Ekiel, Irena; Sulea, Traian; Jansen, Gregor; Kowalik, Maria; Minailiuc, Ovidiu; Cheng, Jing; Harcus, Doreen; Cygler, Miroslaw; Whiteway, Malcolm; Wu, Cunle

Adaptor protein Ste50p links the Ste11p MEKK to the HOG pathway through plasma membrane association

衔接蛋白Ste50p通过与质膜结合,将Ste11p MEKK与HOG通路连接起来。

Wu, Cunle; Jansen, Gregor; Zhang, Jianchun; Thomas, David Y; Whiteway, Malcolm