日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression.

ALDH4A1 作为 MPC 复合物的活性成分，维持线粒体丙酮酸的输入，从而进入 TCA 循环并抑制肿瘤生长

期刊:Nature Cell Biology
影响因子:19.1
doi:10.1038/s41556-025-01651-8
Hsu Che-Chia, Wang Chi-Yun, Manne Rajesh Kumar, Cai Zhen, Penugurti Vasudevarao, Kant Rajni, Bai Ling, Pan Bo-Syong, Chen Tingjin, Chen Yuan-Ru, Wu Hsin-En, Jin Yan, Gu Haiwei, Li Chia-Yang, Lin Hui-Kuan
肿瘤
线粒体
发表日期：2025
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Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting

葡萄糖代谢及其在癌症和免疫调节中的直接作用：代谢靶向的机遇与挑战

期刊:Journal of Biomedical Science
影响因子:12.1
doi:10.1186/s12929-025-01167-1
Pan, Bo-Syong; Hsu, Che-Chia; Wu, Hsin-En; Chen, Yuan-Ru; Zhou, Xiaobo; Wang, Shu-Chi; Li, Chia-Yang; Lin, Hui-Kuan
代谢
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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Nordalbergin Exerts Anti-Neuroinflammatory Effects by Attenuating MAPK Signaling Pathway, NLRP3 Inflammasome Activation and ROS Production in LPS-Stimulated BV2 Microglia

诺达贝金通过减弱LPS刺激的BV2小胶质细胞中的MAPK信号通路、NLRP3炎症小体激活和ROS产生，发挥抗神经炎症作用。

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24087300
Lo, Jung; Wu, Hsin-En; Liu, Ching-Chih; Chang, Kun-Che; Lee, Po-Yen; Liu, Po-Len; Huang, Shu-Pin; Wu, Pei-Chang; Lin, Tzu-Chieh; Lai, Yu-Hung; Chang, Yo-Chen; Chen, Yuan-Ru; Lee, Sheng-I; Huang, Yu-Kai; Wang, Shu-Chi; Li, Chia-Yang
胶质细胞
炎症
炎症/感染
信号转导
神经科学
MAPK/ERK
LRP3
NLRP3
细胞生物学
神经炎症
炎性小体
免疫/内分泌
发表日期：2023
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Protective Effect of Piplartine against LPS-Induced Sepsis through Attenuating the MAPKs/NF-κB Signaling Pathway and NLRP3 Inflammasome Activation

哌拉汀通过减弱MAPKs/NF-κB信号通路和NLRP3炎症小体激活发挥对LPS诱导的脓毒症的保护作用

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph14060588
Huang, Chi-Han; Wang, Shu-Chi; Chen, I-Chen; Chen, Yi-Ting; Liu, Po-Len; Fang, Shih-Hua; Huang, Shu-Pin; Yeh, Hsin-Chih; Liu, Ching-Chih; Lee, Po-Yen; Lin, Tzu-Chieh; Cheng, Wei-Chung; Su, Chia-Cheng; Wu, Hsin-En; Chen, Yuan-Ru; Li, Chia-Yang
炎症
炎症/感染
信号转导
NF-κB
败血症
MAPK/ERK
LRP3
NLRP3
炎性小体
免疫/内分泌
发表日期：2021
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