日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

FBXO2 Alleviates Intervertebral Disc Degeneration via Dual Mechanisms: Activating PINK1-Parkin Mitophagy and Ubiquitinating LCN2 to Suppress Ferroptosis.

FBXO2 通过双重机制缓解椎间盘退变：激活 PINK1-Parkin 线粒体自噬和泛素化 LCN2 以抑制铁死亡。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202506150
Wu Tongde, Wang Yanjin, Shen Beiduo, Guo Kai, Zhu Ziqi, Liang Yongzhou, Zeng Jianhua, Wu Desheng
PINK1
表观遗传
泛素化
NK1
铁死亡
线粒体
Parkin
LCN2
自噬
发表日期：2025
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Passaging Primary Human Bronchial Epithelia Reduces CFTR-Mediated Fluid Transport and Alters mRNA Expression

原代人支气管上皮细胞传代培养会降低CFTR介导的液体转运并改变mRNA表达。

期刊:Cells
影响因子:5.2
doi:10.3390/cells12070997
Wu, Tongde; Wrennall, Joe A; Dang, Hong; Baines, Deborah L; Tarran, Robert
Human
CFTR
细胞生物学
上皮细胞
发表日期：2023
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A SPLUNC1 Peptidomimetic Inhibits Orai1 and Reduces Inflammation in a Murine Allergic Asthma Model

SPLUNC1肽模拟物抑制Orai1并减轻小鼠过敏性哮喘模型中的炎症

期刊:American Journal of Respiratory Cell and Molecular Biology
影响因子:5.3
doi:10.1165/rcmb.2020-0452OC
Wrennall, Joe A; Ahmad, Saira; Worthington, Erin N; Wu, Tongde; Goriounova, Alexandra S; Voeller, Alexis S; Stewart, Ian E; Ghosh, Arunava; Krajewski, Krzysztof; Tilley, Steven L; Hickey, Anthony J; Sassano, M Flori; Tarran, Robert
炎症/感染
Immunology/Inflammation
哮喘
炎症
发表日期：2022
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Construction of a circular RNA-based competing endogenous RNA network to screen biomarkers related to intervertebral disc degeneration

构建基于环状RNA的竞争性内源RNA网络以筛选与椎间盘退变相关的生物标志物

期刊:BMC Musculoskeletal Disorders
影响因子:2.4
doi:10.1186/s12891-022-05579-0
Yu, Bin; Zhu, Ziqi; Hu, Tao; Lu, Jiawei; Shen, Beiduo; Wu, Tongde; Guo, Kai; Chaudhary, Surendra Kumar; Feng, Hang; Zhao, Weidong; Wu, Desheng
发表日期：2022
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Human Umbilical Cord Wharton Jelly Cells Treatment Prevents Osteoporosis Induced by D-Galactose.

人脐带华通氏胶细胞治疗可预防D-半乳糖诱发的骨质疏松症

期刊:International Journal of Clinical Practice
影响因子:2.4
doi:10.1155/2022/4593443
Wang Qiang, Gao Zhiqiang, Guo Kai, Lu Jiawei, Wang Feng, Wu Tongde, Huang Yufeng, Wu Desheng
细胞生物学
骨质疏松
Human
细胞基因治疗
发表日期：2022
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SPLUNC1 is an allosteric modulator of the epithelial sodium channel

SPLUNC1是上皮钠通道的变构调节剂

期刊:FASEB Journal
影响因子:4.2
doi:10.1096/fj.201701126R
Kim, Christine Seulki; Ahmad, Saira; Wu, Tongde; Walton, William G; Redinbo, Matthew R; Tarran, Robert
发表日期：2018
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Withaferin A Analogs That Target the AAA+ Chaperone p97

靶向 AAA+ 分子伴侣 p97 的 Withaferin A 类似物

期刊:ACS Chemical Biology
影响因子:3.8
doi:10.1021/acschembio.5b00367
Tao, Shasha; Tillotson, Joseph; Wijeratne, E M Kithsiri; Xu, Ya-Ming; Kang, MinJin; Wu, Tongde; Lau, Eric C; Mesa, Celestina; Mason, Damian J; Brown, Robert V; Clair, James J La; Gunatilaka, A A Leslie; Zhang, Donna D; Chapman, Eli
发表日期：2015
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Functional chromatography reveals three natural products that target the same protein with distinct mechanisms of action

功能色谱法揭示了三种天然产物，它们靶向同一蛋白质，但作用机制各不相同。

期刊:Chembiochem
影响因子:2.8
doi:10.1002/cbic.201402258
Kang, Min Jin; Wu, Tongde; Wijeratne, E M Kithsiri; Lau, Eric C; Mason, Damian J; Mesa, Celestina; Tillotson, Joseph; Zhang, Donna D; Gunatilaka, A A Leslie; La Clair, James J; Chapman, Eli
发表日期：2014
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KPNA6 (Importin {alpha}7)-mediated nuclear import of Keap1 represses the Nrf2-dependent antioxidant response

KPNA6（输入蛋白α7）介导的Keap1核输入抑制Nrf2依赖的抗氧化反应

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.05036-11
Sun, Zheng; Wu, Tongde; Zhao, Fei; Lau, Alexandria; Birch, Christina M; Zhang, Donna D
发表日期：2011
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A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62

自噬缺陷激活 Nrf2 的非经典机制：Keap1 和 p62 之间的直接相互作用

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.00248-10
Lau, Alexandria; Wang, Xiao-Jun; Zhao, Fei; Villeneuve, Nicole F; Wu, Tongde; Jiang, Tao; Sun, Zheng; White, Eileen; Zhang, Donna D
自噬
发表日期：2010
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