日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification of indoles as potential endogenous ligands of ERRγ and their modulation on drug binding

鉴定吲哚类化合物作为ERRγ的潜在内源性配体及其对药物结合的调节作用

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01550-6
Shuai, Yuan-Yuan; Zhang, Hong-Yang; Chen, Rui; Wang, Bai-Ling; Ding, Ping; Dong, Yan; Sun, Ming-Ze; Wu, Xi-Shan; Xu, Yong; Zhang, Yan; Liu, Jin-Song; Wang, Na; Xu, Ting-Ting
发表日期：2025
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Discovery of 5-imidazole-3-methylbenz[d]isoxazole derivatives as potent and selective CBP/p300 bromodomain inhibitors for the treatment of acute myeloid leukemia.

发现 5-咪唑-3-甲基苯并[d]异恶唑衍生物是治疗急性髓系白血病的强效选择性 CBP/p300 溴结构域抑制剂

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01478-x
Hu Jian-Kang, Tang Xin, Luo Guo-Long, Zhang Cheng, Wu Tian-Bang, Wang Chao, Shen Hui, Zhao Xiao-Fan, Wu Xi-Shan, Smaill Jeff B, Xu Yong, Zhang Yan, Xiang Qiu-Ping
肿瘤
白血病
肿瘤免疫
发表日期：2025
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Liver receptor homolog-1: structures, related diseases, and drug discovery

肝脏受体同源物-1：结构、相关疾病和药物发现

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-024-01276-x
Wu, Tong; Lu, Zhi-Fang; Yu, Hao-Nan; Wu, Xi-Shan; Liu, Yang; Xu, Yong
信号转导
发表日期：2024
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Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer.

发现并药理学表征 1,2,3,4-四氢喹啉衍生物作为 RORγ 反向激动剂对抗前列腺癌

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-024-01274-z
Wu Xi-Shan, Luo Xiao-Yu, Li Cheng-Chang, Zhao Xiao-Fan, Zhang Cheng, Chen Xiao-Shan, Lu Zhi-Fang, Wu Tong, Yu Hao-Nan, Peng Chao, Hu Qing-Qing, Shen Hui, Xu Yong, Zhang Yan
肿瘤
前列腺癌
肿瘤免疫
发表日期：2024
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