日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Membrane disruption, but not metabolic rewiring, is the key mechanism of anticancer-action of FASN-inhibitors: a multi-omics analysis in ovarian cancer

细胞膜破坏而非代谢重编程是FASN抑制剂抗癌作用的关键机制:一项卵巢癌多组学分析

Grunt, Thomas W; Slany, Astrid; Semkova, Mariya; Colomer, Ramón; López-Rodríguez, María Luz; Wuczkowski, Michael; Wagner, Renate; Gerner, Christopher; Stübiger, Gerald

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

脂肪酸合酶抑制剂对受体 PI3K-mTORC1 的多层次抑制对于其对抗卵巢癌细胞的疗效至关重要

Renate Wagner, Gerald Stübiger, Daniel Veigel, Michael Wuczkowski, Peter Lanzerstorfer, Julian Weghuber, Emmanouil Karteris, Karin Nowikovsky, Nastasia Wilfinger-Lutz, Christian F Singer, Ramón Colomer, Bellinda Benhamú, María Luz López-Rodríguez, Peter Valent, Thomas W Grunt