QSP modeling of a transiently inactivating antibody-drug conjugate highlights benefit of short antibody half life.
对瞬时失活抗体-药物偶联物的 QSP 建模突显了抗体半衰期短的优势
期刊:Journal of Pharmacokinetics and Pharmacodynamics
影响因子:2.8
doi:10.1007/s10928-024-09956-1
Khera Eshita, Dharmarajan Lekshmi, Hainzl Dominik, Engelhardt Volker, Vostiarova Helena, Davis John, Ebel Nicolas, Wuersch Kuno, Romanet Vincent, Sharaby Sherif, Kearns Jeffrey D
