Wulff Heike相关文献与解析，生知库 | 链接生命科学的每一步

Nam, Young-Woo; Ramanishka, Alena; Xu, Yang; Yasuda, Rose Marie Haynes; Nasburg, Joshua A; Im, Dohyun; Cui, Meng; Chandy, K George; Wulff, Heike; Zhang, Miao

发表日期：2026

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Kv1.3 as an upstream regulator of oxidative stress-mediated neuroinflammation following organic dust exposure in murine in vitro, ex vivo, and in vivo models.

Kv1.3 作为小鼠体外、离体和体内模型中有机粉尘暴露后氧化应激介导的神经炎症的上游调节因子。

期刊:Frontiers in Toxicology

影响因子:4.6

doi:10.3389/ftox.2026.1765108

Massey Nyzil, Bhat Sanjana Mahadev, Shrestha Denusha, Malovic Emir, Karriker Locke A, Choudhary Shivani, Robertson Alan P, Nguyen Hai Minh, Wulff Heike, Kanthasamy Anumantha G, Charavaryamath Chandrashekhar

神经炎症

神经科学

Immunology/Inflammation

Recent advances in the pharmacology of voltage-gated ion channels

电压门控离子通道药理学的最新进展

期刊:Pharmacological Reviews

影响因子:17.3

doi:10.1016/j.pharmr.2025.100090

Lopez-Mateos, Diego; Harris, Brandon John; Hernández-González, Adriana; Yarov-Yarovoy, Vladimir; Wulff, Heike

发表日期：2025

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Photoisomerization of Azobenzene-Extended Charybdotoxin for the Optical Control of K(v)1.2 Potassium Channel Activity

利用偶氮苯延伸的卡律毒素的光异构化来光学控制K(v)1.2钾通道活性

期刊:Angewandte Chemie-International Edition

影响因子:16.9

doi:10.1002/anie.202423278

Achouba, Yanis; Peres, Basile; Ascoët, Steven; Meudal, Hervé; Caumes, Cécile; Zoukimian, Claude; Millet, Hugo; Choteau-Bodor, Maureen; Carvalhosa, Cathy; Croyal, Mikael; Bouchama, Fella; Wulff, Heike; Téletchéa, Stéphane; Béroud, Rémy; Ishow, Eléna; Landon, Céline; Boumendjel, Ahcène; Montnach, Jérôme; De Waard, Michel

发表日期：2025

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Cryo-EM structures of the small-conductance Ca(2+)-activated K(Ca)2.2 channel

小电导Ca(2+)激活K(Ca)2.2通道的冷冻电镜结构

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-59061-1

Nam, Young-Woo; Im, Dohyun; Garcia, Ana Santa Cruz; Tringides, Marios L; Nguyen, Hai Minh; Liu, Yan; Orfali, Razan; Ramanishka, Alena; Pintilie, Grigore; Su, Chih-Chia; Cui, Meng; Logothetis, Diomedes E; Yu, Edward W; Wulff, Heike; Chandy, K George; Zhang, Miao

发表日期：2025

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Corrigendum to 'Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice' (Br J Anaesth 2020; 125: 298-307)

对“阻断 Kv1.3 钾通道可预防小鼠术后神经炎症和认知能力下降，且不影响伤口愈合”（Br J Anaesth 2020; 125: 298-307）的更正

期刊:British Journal of Anaesthesia

影响因子:9.2

doi:10.1016/j.bja.2025.09.003

Lai, Ieng K; Valdearcos, Martin; Morioka, Kazuhito; Saxena, Sarah; Feng, Xiaomei; Li, Rong; Uchida, Yosuke; Lijun, An; Li, Wei; Pan, Jonathan; Koliwad, Suneil; Marcucio, Ralph; Wulff, Heike; Maze, Mervyn

Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel K(Ca)3.1

选择性1,4-二氢吡啶类钙激活钾通道K(Ca)3.1抑制剂的设计和结构基础

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2425494122

Ong, Seow Theng; Nam, Young-Woo; Nasburg, Joshua A; Ramanishka, Alena; Ng, Xuan Rui; Zhuang, Zhong; Goay, Stephanie Shee Min; Nguyen, Hai M; Singh, Latika; Singh, Vikrant; Rivera, Alicia; Eyster, M Elaine; Xu, Yang; Alper, Seth L; Wulff, Heike; Zhang, Miao; Chandy, K George

发表日期：2025

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Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication

急性有机磷中毒大鼠模型中纤溶酶原激活系统的时空扰动

期刊:Acta Neuropathologica Communications

影响因子:5.7

doi:10.1186/s40478-025-01979-0

Blackmon, Thomas J; MacMahon, Jeremy A; Bernardino, Pedro N; Hogans, Ryan E; Cheng, Mei-Yun; Vu, Joan; Lee, Ruth Diana; Saito, Naomi H; Grodzki, Ana Cristina; Bruun, Donald A; Wulff, Heike; Woolard, Kevin D; Brooks-Kayal, Amy; Harvey, Danielle J; Gorin, Fredric A; Lein, Pamela J

Rat

发表日期：2025

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Corrigendum: Riluzole attenuates acute neural injury and reactive gliosis, hippocampal-dependent cognitive impairments and spontaneous recurrent generalized seizures in a rat model of temporal lobe epilepsy

更正：利鲁唑可减轻颞叶癫痫大鼠模型中的急性神经损伤和反应性胶质增生、海马依赖性认知障碍以及自发性复发性全身性癫痫发作。

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1592653

Kyllo, Thomas; Allocco, Dominic; Vande Hei, Laine; Wulff, Heike; Erickson, Jeffrey D

Administration of the K(Ca) channel activator SKA-31 improves endothelial function in the aorta of atherosclerosis-prone mice.

施用 K(Ca) 通道激活剂 SKA-31 可改善易患动脉粥样硬化小鼠主动脉的内皮功能

期刊:Frontiers in Pharmacology

影响因子:4.8

doi:10.3389/fphar.2025.1545050

Vera O Daniel, Mishra Ramesh C, Khaddaj-Mallat Rayan, Hamm Liam, Almarzouq Barak, Chen Yong-Xiang, Belke Darrell D, Singh Latika, Wulff Heike, Braun Andrew P

Structural basis for the subtype-selectivity of K(Ca)2.2 channel activators

K(Ca)2.2通道激活剂亚型选择性的结构基础

Kv1.3 as an upstream regulator of oxidative stress-mediated neuroinflammation following organic dust exposure in murine in vitro, ex vivo, and in vivo models.

Kv1.3 作为小鼠体外、离体和体内模型中有机粉尘暴露后氧化应激介导的神经炎症的上游调节因子。

Recent advances in the pharmacology of voltage-gated ion channels

电压门控离子通道药理学的最新进展

Photoisomerization of Azobenzene-Extended Charybdotoxin for the Optical Control of K(v)1.2 Potassium Channel Activity

利用偶氮苯延伸的卡律毒素的光异构化来光学控制K(v)1.2钾通道活性

Cryo-EM structures of the small-conductance Ca(2+)-activated K(Ca)2.2 channel

小电导Ca(2+)激活K(Ca)2.2通道的冷冻电镜结构

Corrigendum to 'Blocking Kv1.3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice' (Br J Anaesth 2020; 125: 298-307)

对“阻断 Kv1.3 钾通道可预防小鼠术后神经炎症和认知能力下降，且不影响伤口愈合”（Br J Anaesth 2020; 125: 298-307）的更正

Design and structural basis of selective 1,4-dihydropyridine inhibitors of the calcium-activated potassium channel K(Ca)3.1

选择性1,4-二氢吡啶类钙激活钾通道K(Ca)3.1抑制剂的设计和结构基础

Spatiotemporal perturbations of the plasminogen activation system in a rat model of acute organophosphate intoxication

急性有机磷中毒大鼠模型中纤溶酶原激活系统的时空扰动

Corrigendum: Riluzole attenuates acute neural injury and reactive gliosis, hippocampal-dependent cognitive impairments and spontaneous recurrent generalized seizures in a rat model of temporal lobe epilepsy

更正：利鲁唑可减轻颞叶癫痫大鼠模型中的急性神经损伤和反应性胶质增生、海马依赖性认知障碍以及自发性复发性全身性癫痫发作。

Administration of the K(Ca) channel activator SKA-31 improves endothelial function in the aorta of atherosclerosis-prone mice.

施用 K(Ca) 通道激活剂 SKA-31 可改善易患动脉粥样硬化小鼠主动脉的内皮功能