Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates
通过自裂解磷酰胺递送含羟基药物,扩大抗体药物偶联物的有效载荷范围
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68605-y
Ochtrop, Philipp; Jagtap, Anil P; Felber, Jan G; Vogt, Simon; Herterich, Sarah; Mai, Isabelle; Cyprys, Philipp; Schmitt, Saskia; Payer, Sarah; Kitowski, Annabel; Wunder, Swetlana; Machui, Paul; Brandmeier, Julia; Leonardi, Natascia; Poliak, Elizaveta; Hackenberger, Christian P R; Marcq, Olivier; Schumacher, Dominik; Helma, Jonas; Vogl, Annette M; Kasper, Marc-André