Patient-derived tumoroids from CIC::DUX4 rearranged sarcoma identify MCL1 as a therapeutic target.
从 CIC::DUX4 重排肉瘤中分离出的患者来源的肿瘤样细胞确定 MCL1 为治疗靶点
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-62629-6
Breunis Willemijn, Brack Eva, Ehlers Anna C, Bechtold Ingrid, Kisele Samanta, Wurth Jakob, Mous Lieke, Zabele Dorita, Steffen Fabio, Zahnow Felina, Britschgi Christian, Bankel Lorenz, Rothermundt Christian, Vetter Cornelia, Müller Daniel, Botter Sander, Pauli Chantal, Bode Peter, Rinner Beate, Bourquin Jean-Pierre, Roessler Jochen, Grünewald Thomas G P, Schäfer Beat W, Surdez Didier, Wachtel Marco
