日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Safety and biologic activity of a bispecific T cell receptor targeting HIV Gag in males living with HIV: a first-in-human trial.

针对 HIV Gag 的双特异性 T 细胞受体在 HIV 感染男性中的安全性和生物活性:首次人体试验。

Vandekerckhove Linos, Fox Julie, Mora-Peris Borja, Navarro Jordi, Allard Sabine D, Uriel Alison J, Moreno Guillén Santiago, Boffito Marta, Post Frank A, Estrada Vicente, Mothe Beatriz, Delporte Mareva, Benlahrech Adel, Rahman Haseeb, Clubley James, Treveil Agatha, Chamberlain Jonathan, Harrison Rory, Hock Miriam, Yuan Yuan, Wustner Jason, Moureau Sylvie, Whale Andrew D, Wallace Zoë, Singh Praveen K, Titanji Kehmia, Dorrell Lucy, Fidler Sarah

Phase 1 study of IMCnyeso, a T cell receptor bispecific ImmTAC targeting NY-ESO-1-expressing malignancies

IMCnyeso 的 I 期研究,IMCnyeso 是一种靶向表达 NY-ESO-1 的恶性肿瘤的 T 细胞受体双特异性 ImmTAC。

Juanita S Lopez,Mohammed Milhem,Marcus O Butler,Fiona Thistlethwaite,Brian A Van Tine,Sandra P D'Angelo,Melissa L Johnson,Takami Sato,Hendrik-Tobias Arkenau,Ramakrishna Edukulla,Jason Wustner,Shannon Marshall,Jordi Rodon

Population pharmacokinetics and exposure-response relationship of amatuximab, an anti-mesothelin monoclonal antibody, in patients with malignant pleural mesothelioma and its application in dose selection

阿马妥昔单抗(一种抗间皮素单克隆抗体)在恶性胸膜间皮瘤患者中的群体药代动力学和暴露-反应关系及其在剂量选择中的应用

Gupta, Anubha; Hussein, Ziad; Hassan, Raffit; Wustner, Jason; Maltzman, Julia D; Wallin, Bruce A

Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature

通过抗体介导的内化靶向内皮唾液酸蛋白/CD248会导致周细胞成熟受损和肿瘤微血管功能障碍

Katherine Rybinski, Hongxia Z Imtiyaz, Barrie Mittica, Brian Drozdowski, James Fulmer, Keiji Furuuchi, Shawn Fernando, Marianne Henry, Qimin Chao, Brad Kline, Earl Albone, Jason Wustner, JianMin Lin, Nicholas C Nicolaides, Luigi Grasso, Yuhong Zhou

A white paper--consensus and recommendations of a global harmonization team on assessing the impact of immunogenicity on pharmacokinetic measurements

白皮书——全球协调小组关于评估免疫原性对药代动力学测量影响的共识和建议

J M Sailstad, L Amaravadi, A Clements-Egan, B Gorovits, H A Myler, R C Pillutla, S Pursuhothama, M Putman, M K Rose, K Sonehara, L Tang, J T Wustner; Global Bioanalysis Consortium

Population pharmacokinetics of farletuzumab, a humanized monoclonal antibody against folate receptor alpha, in epithelial ovarian cancer

法妥珠单抗(一种针对叶酸受体α的人源化单克隆抗体)在卵巢上皮癌中的群体药代动力学研究

Farrell, Colm; Schweizer, Charles; Wustner, Jason; Weil, Susan; Namiki, Masayuki; Nakano, Tomohisa; Nakai, Kenya; Phillips, Martin D

Transferrin fusion technology: a novel approach to prolonging biological half-life of insulinotropic peptides

转铁蛋白融合技术:延长胰岛素促泌肽生物半衰期的新方法

Byung-Joon Kim, Jie Zhou, Bronwen Martin, Olga D Carlson, Stuart Maudsley, Nigel H Greig, Mark P Mattson, Ellen E Ladenheim, Jay Wustner, Andrew Turner, Homayoun Sadeghi, Josephine M Egan