Wyatt Michael D相关文献与解析，生知库 | 链接生命科学的每一步

Collateral damage of NUDT15 deficiency in cancer provides a cancer pharmacogenetic therapeutic window with thiopurines

NUDT15 缺陷导致的癌症附带损害为硫嘌呤类药物提供了一个癌症药理遗传学治疗窗口。

期刊:

影响因子:

doi:10.1101/2024.04.08.588560

Massey, Jacob C; Magagnoli, Joseph; Sutton, S Scott; Buckhaults, Phillip J; Wyatt, Michael D

Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among patients with human immunodeficiency virus

接触可穿过血脑屏障的血管紧张素转换酶抑制剂与人类免疫缺陷病毒感染者患痴呆症的风险

期刊:

影响因子:

doi:10.1101/2024.01.16.24301275

Cummings, Tammy H; Magagnoli, Joseph; Sikirzhytskaya, Aliaksandra; Tyagin, Ilya; Safro, Ilya; Wyatt, Michael D; Shtutman, Michael; Sutton, S Scott

Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among people with HIV

接触可穿过血脑屏障的血管紧张素转换酶抑制剂与艾滋病毒感染者患痴呆症的风险之间的关系

期刊:AIDS

影响因子:

doi:10.1097/QAD.0000000000004009

Cummings, Tammy H; Magagnoli, Joseph; Sikirzhytskaya, Aliaksandra; Tyagin, Ilya; Safro, Ilya; Wyatt, Michael D; Shtutman, Michael S; Sutton, S Scott

Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

通过 REPLACE 筛选鉴定的 PLK1 polo box 结构域非肽类抑制剂的结构-活性和机制研究

期刊:European Journal of Medicinal Chemistry

影响因子:5.9

doi:10.1016/j.ejmech.2021.113926

Craig, Sandra N; Baxter, Merissa; Chapagai, Danda; Stafford, Jessy M; Nurmemmedov, Elmar; Altomare, Diego; Wyatt, Michael D; McInnes, Campbell

PLK1

发表日期：2022

文献求助收藏

Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells

靶向 Polo-Box 结构域的非肽类 PLK1 抑制剂可阻断激酶活性，诱导其降解并产生靶向耐药细胞。

期刊:Journal of Medicinal Chemistry

影响因子:6.8

doi:10.1021/acs.jmedchem.1c00133

Chapagai, Danda; Ramamoorthy, Gurusankar; Varghese, Jessy; Nurmemmedov, Elmar; McInnes, Campbell; Wyatt, Michael D

Improving oncology biosimilar launches in the EU, the USA, and Japan: an updated Policy Review from the Southern Network on Adverse Reactions

改善欧盟、美国和日本肿瘤生物类似药的上市：南方不良反应网络最新政策审查

期刊:Lancet Oncology

影响因子:35.9

doi:10.1016/S1470-2045(20)30485-X

Bennett, Charles L; Schoen, Martin W; Hoque, Shamia; Witherspoon, Bartlett J; Aboulafia, David M; Hwang, Catherine S; Ray, Paul; Yarnold, Paul R; Chen, Brian K; Schooley, Benjamin; Taylor, Matthew A; Wyatt, Michael D; Hrushesky, William J; Yang, Y Tony

Clinical significance of a pvrl 4 encoded gene Nectin-4 in metastasis and angiogenesis for tumor relapse.

pvrl 4 编码基因 Nectin-4 在肿瘤转移和血管生成中对肿瘤复发的临床意义

期刊:Journal of Cancer Research and Clinical Oncology

影响因子:2.8

doi:10.1007/s00432-019-03055-2

Sethy Chinmayee, Goutam Kunal, Nayak Deepika, Pradhan Rajalaxmi, Molla Sefinew, Chatterjee Subhajit, Rout Niranjan, Wyatt Michael D, Narayan Satya, Kundu Chanakya Nath

Structural regulation of PLK1 activity: implications for cell cycle function and drug discovery

PLK1活性的结构调控：对细胞周期功能和药物发现的意义

Schizophrenia, Off-Label Antipsychotics, and Dementia Risk in People With HIV

精神分裂症、非适应症抗精神病药物和艾滋病毒感染者痴呆风险

Synthesis and Monoamine Oxidase Inhibitory Activity of Halogenated Flavones

卤代黄酮的合成及其单胺氧化酶抑制活性

Collateral damage of NUDT15 deficiency in cancer provides a cancer pharmacogenetic therapeutic window with thiopurines

NUDT15 缺陷导致的癌症附带损害为硫嘌呤类药物提供了一个癌症药理遗传学治疗窗口。

Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among patients with human immunodeficiency virus

接触可穿过血脑屏障的血管紧张素转换酶抑制剂与人类免疫缺陷病毒感染者患痴呆症的风险

Exposure to angiotensin-converting enzyme inhibitors that cross the blood-brain barrier and the risk of dementia among people with HIV

接触可穿过血脑屏障的血管紧张素转换酶抑制剂与艾滋病毒感染者患痴呆症的风险之间的关系

Structure-activity and mechanistic studies of non-peptidic inhibitors of the PLK1 polo box domain identified through REPLACE

通过 REPLACE 筛选鉴定的 PLK1 polo box 结构域非肽类抑制剂的结构-活性和机制研究

Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells

靶向 Polo-Box 结构域的非肽类 PLK1 抑制剂可阻断激酶活性，诱导其降解并产生靶向耐药细胞。

Improving oncology biosimilar launches in the EU, the USA, and Japan: an updated Policy Review from the Southern Network on Adverse Reactions

改善欧盟、美国和日本肿瘤生物类似药的上市：南方不良反应网络最新政策审查

Clinical significance of a pvrl 4 encoded gene Nectin-4 in metastasis and angiogenesis for tumor relapse.

pvrl 4 编码基因 Nectin-4 在肿瘤转移和血管生成中对肿瘤复发的临床意义