日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Convergent antigenic drift of the influenza hemagglutinin lateral patch across time and species

流感病毒血凝素侧斑在时间和物种间的趋同抗原漂移

Guenaga, Javier; Adori, Monika; Bale, Shridhar; Phulera, Swastik; Zygouras, Ioannis; Schleich, Fabian-Alexander; Dopico, Xaquin Castro; Agrawal, Sashank; Ota, Miyo; Wilson, Richard; Cluff, Jocelyn; Dzvelaia, Tamar; Mandolesi, Marco; Walsh, Agnes; Melo, Mariane B; Verkoczy, Laurent; Irvine, Darrell J; Corcoran, Martin; Wilson, Ian A; Carnathan, Diane; Silvestri, Guido; Ward, Andrew B; Ozorowski, Gabriel; Karlsson Hedestam, Gunilla B; Wyatt, Richard T; Lemus-Reyes, Jordan I; Fernandez-Quintero, Monica L; Ayala, Edgardo; Swanson, Olivia M; Good, Marina R; Ji, Wei; Suja, Devika; Han, Julianna; Ward, Andrew B; Guthmiller, Jenna J

Rational design of flavivirus E protein vaccine optimizes immunogenicity and mitigates antibody dependent enhancement risk.

黄病毒E蛋白疫苗的合理设计可优化免疫原性并降低抗体依赖性增强风险。

Wang Yimeng, Galkin Andrey, Shang Xiaoran, Marin Alexander, Jin Shaohua, Ye Ting-Juan, Bale Shridhar, Chiang Chi-I, Chowdhury Ananda, Chenine Agnes L, Turonis Ashley, Greenhouse Jack, Stone Rebecca, Wear Jaclyn, Kar Swagata, Andersen Hanne, Huang Yan-Jang S, Vanlandingham Dana L, Higgs Stephen, Lapidus Rena G, Fuerst Thomas, Weber David J, Wyatt Richard T, Iffland Christel, Pierson Theodore C, Andrianov Alexander K, Pozharski Edwin, Li Yuxing

Antigen persistence and TLR stimulation contribute to induction of a durable HIV-1-specific neutralizing antibody response.

抗原持续存在和 TLR 刺激有助于诱导持久的 HIV-1 特异性中和抗体反应

Matsuda Kenta, Harrison Mitra, Wettstein Eleanor, Pederson Jessica, Pullano Alyssa A, Bolkhovitinov Lyuba, Kim Breanna, Steinberg Isabel, Griesman Trevor, Stuccio Sarah, Rogan Daniel, Patamawenu Andy, Shofner Tulley, Wright Nathaniel E, Webber Jonathan D, Van't Veer Freya, Roenicke Rachel, Koory Emma, Roeder Peyton M, Ober Ellison, Leach Benjamin, Tsybovsky Yaroslav, Stephens Tyler, Del Moral-Sanchez Ivan, Bontjer Ilja, McGinnes-Cullen Lori W, Chu Eric, Liang Jason, Torres Jonathan L, Lin Ryan N, Tran Andy S, Dziubla Gabrielle, Serebryannyy Leonid, Narpala Sandeep, Lin Bob, Castro Mike, Ozorowski Gabriel, Ward Andrew B, Sanders Rogier W, Kwong Peter D, Guenaga Javier, Wyatt Richard, Morrison Trudy, Connors Mark

Molecular parameters governing antibody FcγR signaling and effector functions in the context of HIV envelope

HIV包膜蛋白背景下调控抗体FcγR信号传导和效应功能的分子参数

Bick, Michael V; Puig, Eduard; Beauparlant, David; Nedellec, Rebecca; Burton, Iszac; Ardaghi, Keihvan; Zalunardo, Thea R; Bastidas, Raiza; Li, Xuduo; Guenaga, Javier; Lee, Wen-Hsin; Wyatt, Richard; Zhu, Wenwen; Crispin, Max; Ozorowski, Gabriel; Ward, Andrew B; Burton, Dennis R; Hangartner, Lars

Accelerated cGMP production of near-native HIV-1 Env trimers following electroporation transfection and immunogenicity analysis

利用电穿孔转染和免疫原性分析,加速cGMP生产接近天然HIV-1 Env三聚体。

Bale, Shridhar; Gustchina, Elena; Guenaga, Javier; Ayala, Victor; Lee, Wen-Hsin; Ozorowski, Gabriel; Whitney, Stephen; Wilson, Richard; Baboo, Sabyasachi; Diedrich, Jolene K; Doyle, Esmeralda D; Hudacik, Lauren; Ben-Akiva, Elana; Rodrigues, Kristen A; Irvine, Darrell J; Yates, John R 3rd; Paulson, James C; Ward, Andrew B; Fouts, Timothy; Wyatt, Richard T

Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.

HIV Env 疫苗诱导的 B 细胞反应的广泛传播和克隆内成熟

Phad Ganesh E, Pushparaj Pradeepa, Tran Karen, Dubrovskaya Viktoriya, Àdori Monika, Martinez-Murillo Paola, Vázquez Bernat Néstor, Singh Suruchi, Dionne Gilman, O'Dell Sijy, Bhullar Komal, Narang Sanjana, Sorini Chiara, Villablanca Eduardo J, Sundling Christopher, Murrell Benjamin, Mascola John R, Shapiro Lawrence, Pancera Marie, Martin Marcel, Corcoran Martin, Wyatt Richard T, Karlsson Hedestam Gunilla B

Correction for Khan et al., "Targeting the HIV-1 Spike and Coreceptor with Bi- and Trispecific Antibodies for Single-Component Broad Inhibition of Entry"

对 Khan 等人的论文“利用双特异性和三特异性抗体靶向 HIV-1 刺突蛋白和辅助受体以实现单组分广谱入侵抑制”的更正

Khan, Salar N; Sok, Devin; Tran, Karen; Movsesyan, Arlette; Dubrovskaya, Viktoriya; Burton, Dennis R; Wyatt, Richard T

The role of genetic variation in DGKK on moderate and severe hypospadias

DGKK基因变异对中重度尿道下裂的影响

Richard, Melissa A; Sok, Pagna; Canon, Stephen; Brown, Austin L; Peckham-Gregory, Erin C; Nembhard, Wendy N; Carmichael, Suzan L; Ehli, Erik A; Kallsen, Noah A; Peyton, Shanna A; Davies, Gareth E; Patel, Ashay; Zamilpa, Ismael; Wyatt, Richard A; Hobbs, Charlotte A; Scheurer, Michael E; Lupo, Philip J

Preventing acute asthmatic symptoms by targeting a neuronal mechanism involving carotid body lysophosphatidic acid receptors

通过靶向涉及颈动脉体溶血磷脂酸受体的神经机制来预防急性哮喘症状

Nicholas G Jendzjowsky, Arijit Roy, Nicole O Barioni, Margaret M Kelly, Francis H Y Green, Christopher N Wyatt, Richard L Pye, Luana Tenorio-Lopes, Richard J A Wilson

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model

在野生型动物模型中诱导针对 HIV 包膜三聚体 V2 顶端的中和抗体

Voss, James E; Andrabi, Raiees; McCoy, Laura E; de Val, Natalia; Fuller, Roberta P; Messmer, Terrence; Su, Ching-Yao; Sok, Devin; Khan, Salar N; Garces, Fernando; Pritchard, Laura K; Wyatt, Richard T; Ward, Andrew B; Crispin, Max; Wilson, Ian A; Burton, Dennis R