TRIM68 negatively regulates IFN-β production by degrading TRK fused gene, a novel driver of IFN-β downstream of anti-viral detection systems.
TRIM68 通过降解 TRK 融合基因来负调控 IFN-β 的产生，TRK 融合基因是抗病毒检测系统下游 IFN-β 的一种新型驱动因子
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0101503
Wynne Claire, Lazzari Elisa, Smith Siobhán, McCarthy Eoghan M, Nà Gabhann Joan, Kallal Lara E, Higgs Rowan, Greco Angela, Cryan Sally Ann, Biron Christine A, Jefferies Caroline A
