Spatial multi-omics reveals the potential involvement of SPP1(+) fibroblasts in determining metabolic heterogeneity and promoting metastatic growth of colorectal cancer liver metastasis.
空间多组学揭示了 SPP1(+) 成纤维细胞在决定代谢异质性和促进结直肠癌肝转移转移生长方面的潜在作用。
期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.05.004
Gao Yuzhen, Zhang Xiuping, Xia Shenglong, Chen Qing, Tong Qingchao, Yu Shaobo, An Rui, Cheng Cheng, Zou Wenbo, Liang Leilei, Xie Xinyou, Song Zhangfa, Liu Rong, Zhang Jun