日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PTEN Loss Promotes PI3Kβ Phosphorylation and EPHA2/SRC/p-PI3KβY962 Complex Assembly to Drive Tumorigenesis.

PTEN 缺失促进 PI3Kβ 磷酸化和 EPHA2/SRC/p-PI3KβY962 复合物组装,从而驱动肿瘤发生。

Tang Shuang, Zhou Qian, Bergholz Johann S, Jiang Tao, Wang Weihua, Ji Renlei, Huang Wendi, Wu Jiachen, Li Yutong, Wan Xiaochun, He Xiadi, Jing Qianchen, Sun Menghong, Johnson Jared L, Yaron-Barir Tomer M, Li Da-Qiang, Dai Bo, Wang Zefeng, Li Xiaoling, Cantley Lewis C, Roberts Thomas M, Zhao Jean J

Lysine vitcylation is a vitamin C-derived protein modification that enhances STAT1-mediated immune response.

赖氨酸维生素C化是一种维生素C衍生的蛋白质修饰,可增强STAT1介导的免疫反应

He Xiadi, Wang Qiwei, Cheng Xin, Wang Weihua, Li Yutong, Nan Yabing, Wu Jiang, Xiu Bingqiu, Jiang Tao, Bergholz Johann S, Gu Hao, Chen Fuhui, Fan Guangjian, Sun Lianhui, Xie Shaozhen, Zou Junjie, Lin Sheng, Wei Yun, Lee James, Asara John M, Zhang Ke, Cantley Lewis C, Zhao Jean J

Epidemiological characteristics of pediatric trauma and the role of the Injury Severity Score in predicting mortality risk: a multicenter study

儿童创伤的流行病学特征及损伤严重程度评分在预测死亡风险中的作用:一项多中心研究

Bao, Yiyao; Zhao, Xiadi; Guan, Lijun; Dai, Lingling; Tan, Linhua

IRG1/itaconate/NRF2/GSH axis in tumor-associated macrophages drives therapy resistance and immune evasion in BRCA1-deficient breast cancer.

肿瘤相关巨噬细胞中的 IRG1/衣康酸/NRF2/GSH 轴驱动 BRCA1 缺陷型乳腺癌的治疗耐药性和免疫逃逸。

Nan Yabing, O'keefe Sophie, He Xiadi, Luo Qingyu, Wu Xiaowei, Ni Jing, Zou Yutian, Meade Jerryd Marcus, Li Yutong, Ji Renlei, Mohammad Anwaruddin, Kumar Pankaj, Wang Qiwei, Zhao Jean J

Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation

缺氧诱导线粒体蛋白质乳酸化以限制氧化磷酸化

Yunzi Mao #, Jiaojiao Zhang #, Qian Zhou #, Xiadi He #, Zhifang Zheng, Yun Wei, Kaiqiang Zhou, Yan Lin, Haowen Yu, Haihui Zhang, Yineng Zhou, Pengcheng Lin, Baixing Wu, Yiyuan Yuan, Jianyuan Zhao, Wei Xu, Shimin Zhao

Interventional embolisation for patients with cirrhosis and recurrent or persistent hepatic encephalopathy related to spontaneous portosystemic shunts: protocol for a prospective, non-randomised controlled study

针对伴有自发性门体分流的肝硬化和复发性或持续性肝性脑病患者的介入栓塞治疗:一项前瞻性、非随机对照研究方案

Ke, Qiao; Lin, Ting; Lei, Xiaojuan; Weng, Xiadi; He, Jian; Huang, Xinhui; Li, Ling; Guo, Wu-Hua

Integration Analysis of Single-Cell Multi-Omics Reveals Prostate Cancer Heterogeneity

单细胞多组学整合分析揭示前列腺癌异质性

Xiaojie Bian, Wenfeng Wang, Mierxiati Abudurexiti, Xingming Zhang, Weiwei Ma, Guohai Shi, Leilei Du, Midie Xu, Xin Wang, Cong Tan, Hui Sun, Xiadi He, Chenyue Zhang, Yao Zhu, Min Zhang, Dingwei Ye, Jianhua Wang

Lactate regulates cell cycle by remodelling the anaphase promoting complex

乳酸通过重塑后期促进复合物来调节细胞周期。

Weihai Liu #,Yun Wang #,Luiz H M Bozi #,Patrick D Fischer #,Mark P Jedrychowski,Haopeng Xiao,Tao Wu,Narek Darabedian,Xiadi He,Evanna L Mills,Nils Burger,Sanghee Shin,Anita Reddy,Hans-Georg Sprenger,Nhien Tran,Sally Winther,Stephen M Hinshaw,Jingnan Shen,Hyuk-Soo Seo,Kijun Song,Andrew Z Xu,Luke Sebastian,Jean J Zhao,Sirano Dhe-Paganon,Jianwei Che,Steven P Gygi,Haribabu Arthanari,Edward T Chouchani

In natura heart rate variability predicts subsequent alcohol use in individuals in early recovery from alcohol use disorder

自然状态下,心率变异性可以预测酒精使用障碍早期康复者随后的酒精使用情况。

Eddie, David; Wieman, Sarah; Pietrzak, Agata; Zhai, Xiadi

STING agonism reprograms tumor-associated macrophages and overcomes resistance to PARP inhibition in BRCA1-deficient models of breast cancer

STING激动剂可重编程肿瘤相关巨噬细胞,并克服BRCA1缺陷型乳腺癌模型中对PARP抑制剂的耐药性。

Qiwei Wang # ,Johann S Bergholz # ,Liya Ding ,Ziying Lin ,Sheheryar K Kabraji ,Melissa E Hughes ,Xiadi He ,Shaozhen Xie ,Tao Jiang ,Weihua Wang ,Jason J Zoeller ,Hye-Jung Kim ,Thomas M Roberts ,Panagiotis A Konstantinopoulos ,Ursula A Matulonis ,Deborah A Dillon ,Eric P Winer ,Nancy U Lin ,Jean J Zhao