Xian Xunde相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Vascular smooth muscle cell-derived KIF13B inhibits proinflammatory responses to protect against atherosclerosis

血管平滑肌细胞衍生的KIF13B抑制促炎反应，从而起到预防动脉粥样硬化的作用。

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI194175

Miao, Guolin; Han, Yufei; Chen, Jingxuan; Liu, Yiran; Zhang, Ge; Pei, Shaotong; Zhao, Yinqi; Xu, Yitong; Zheng, Liwen; Li, Zhaoling; Liu, Xiangru; Shi, Sijing; Kang, Xuya; Liu, Yahan; Zhang, Ling; Huang, Wei; Wang, Yuhui; Tang, Junnan; Dong, Erdan; Xian, Xunde

细胞生物学

动脉粥样硬化

发表日期：2026

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Apolipoprotein C3 exacerbates vascular calcification by promoting ferroptosis via the TLR2/AMPK pathway in vascular smooth muscle cells.

载脂蛋白 C3 通过 TLR2/AMPK 通路促进血管平滑肌细胞发生铁死亡，从而加剧血管钙化。

期刊:Redox Biology

影响因子:11.9

doi:10.1016/j.redox.2026.104088

Zhou Zihao, Chen Jinxuan, Wang Huan, Han Yufei, Liu Changyun, Shen Qiang, Dong Zhao, Lu Kaikai, Zhai Chao, Xu Yitong, Zhang Lianxin, He Lei, Fang Yuan, Zhang Ling, Wang Yuhui, Xian Xunde, Yao Lin, Dong Erdan, Huang Wei

细胞生物学

发表日期：2026

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SiRNA-based inactivation of Angptl3 alleviates high-fat diet-induced MAFLD and atherosclerosis in LDLR-deficient hamsters

基于siRNA的Angptl3失活可减轻LDLR缺陷仓鼠高脂饮食诱导的MAFLD和动脉粥样硬化

期刊:Lipids in Health and Disease

影响因子:4.2

doi:10.1186/s12944-026-02916-3

Zhang, Xiaohong; Han, Yufei; Zheng, Liwen; He, Xiaokui; Pu, Yungang; Wei, Lili; Wang, Yuhui; Xian, Xunde

动脉粥样硬化

发表日期：2026

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Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9

利用 CRISPR/Cas9 技术对受精卵进行显微注射，生成带有条件性等位基因的叙利亚金仓鼠

期刊:Animal Models and Experimental Medicine

影响因子:3.4

doi:10.1002/ame2.70107

Chen, Wei; Zhang, Xu; Fan, Rui; Li, Xia; Guan, Feifei; Wan, Gefan; Kong, Weining; Qi, Xiaolong; Pan, Shuo; Shi, Sijing; Su, Yuanlong; Gao, Shan; Huang, Wei; Xian, Xunde; Liu, Jiangning; Wang, Yuhui; Ma, Yuanwu

发表日期：2026

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Depletion of Kif13b promotes neuroinflammatory attack against myelin in an experimental autoimmune encephalomyelitis mouse model

在实验性自身免疫性脑脊髓炎小鼠模型中，Kif13b 的缺失会促进针对髓鞘的神经炎症攻击。

期刊:Genes and Diseases

doi:10.1016/j.gendis.2025.101946

Chen, Jingxuan; Xu, Yitong; Miao, Guolin; Zheng, Liwen; Lu, Kaikai; Zhang, Wenxi; Huang, Wei; Wang, Yuhui; Xian, Xunde

免疫/内分泌

发表日期：2026

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KIF13B Attenuates Sepsis-Induced Myocardial Dysfunction through the Stabilization of PLIN5

KIF13B通过稳定PLIN5减轻脓毒症引起的心肌功能障碍

doi:10.34133/research.1033

Zhang, Lianxin; Miao, Guolin; Mei, Si; Han, Yufei; Xu, Yitong; Zhang, Wenxi; Chen, Jingxuan; Lu, Kaikai; Zhao, Yinqi; Zhou, Zihao; Chen, Jinxuan; Guo, Jiabao; Lai, Pingping; Lam, Sin Man; Shui, Guanghou; Zhang, Ling; Zhang, Weiguang; Huang, Wei; Wang, Yuhui; Xian, Xunde

发表日期：2026

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SR-A3 suppresses AKT activation to protect against MAFLD by inhibiting XIAP-mediated PTEN degradation.

SR-A3 抑制 AKT 激活，从而抑制 XIAP 介导的 PTEN 降解，以防止 MAFLD

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-57585-0

Lai Pingping, Miao Guolin, Zhao Yinqi, Han Yufei, Li Yanwei, Liu Yiran, Guo Jiabao, Zhang Wenxi, Guo Xin, Xu Yitong, Zhang Lianxin, Chen Gonglie, Zhou Zihao, Mei Si, Chen Jingxuan, Chen Jinxuan, Xu Luzheng, Zhang Chong, Ding Yang, Dou Xiaoguang, Wen Shengmei, Lam Sin Man, Shui Guanghou, Wang Yuhui, Huang Wei, Zhao Dongyu, Xian Xunde

发表日期：2025

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IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPKÎ± to attenuate hypercholesterolemia.

IMM-H007 通过激活 AMPKÎ± 来促进肝脏胆固醇和甘油三酯代谢，从而减轻高胆固醇血症

期刊:Acta Pharmaceutica Sinica B

影响因子:14.6

doi:10.1016/j.apsb.2025.05.015

Li Jiaqi, Wang Mingchao, Qu Kai, Sun Yuyao, Yin Zequn, Dong Na, Sun Xin, Xu Yitong, Chen Liang, Zhang Shuang, Xian Xunde, Xu Suowen, Ma Likun, Duan Yajun, Zhu Haibo

发表日期：2025

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Macrophage-derived KIF13B interacts with USP9X to attenuate abdominal aortic aneurysm development by potentiating TFEB stability

巨噬细胞来源的KIF13B与USP9X相互作用，通过增强TFEB稳定性来减弱腹主动脉瘤的发展。

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.118958

Chen, Jingxuan; Xu, Yitong; Yu, Huahui; Liu, Yiran; Miao, Guolin; Han, Yufei; Zheng, Liwen; Cai, Zeyu; Zhou, Zihao; Chen, Jinxuan; Shi, Sijing; Lai, Pingping; Zhang, Wenxi; Zhang, Lianxin; Mei, Si; Zhao, Yinqi; Zhang, Ling; Huang, Wei; Wang, Yuhui; Zhao, Dongyu; Kong, Wei; Qin, Yanwen; Dong, Erdan; Xian, Xunde

细胞生物学

免疫/内分泌

发表日期：2025

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A natural small molecule isoginkgetin alleviates hypercholesterolemia and atherosclerosis by targeting ACLY.

天然小分子异银杏黄素通过靶向ACLY缓解高胆固醇血症和动脉粥样硬化

期刊:Theranostics

影响因子:13.3

doi:10.7150/thno.105782

Zhang Zhidan, Chen Meijie, Xu Yitong, Wang Zhihua, Liu Zhenghong, He Chenyang, Zhang Fanshun, Feng Xiaojun, Ni Xiayun, Chen Yuanli, Wang Jixia, Liang Xinmiao, Xie Zhifu, Li Jingya, Banach Maciej, Pelisek Jaroslav, Huo Yuqing, Hu Yunhui, Evans Paul C, Wang Li, Tian Xiao-Yu, Xiao Jianbo, Shang Yuhua, Zheng Yijun, Xian Xunde, Weng Jianping, Xu Suowen

动脉粥样硬化

发表日期：2025

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