日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TGF-β Regulates CD8(+) T Cell Memory by Triggering mTORC1(Weak)-Mediated Activation of the Transcriptional FOXO1-TCF1-Eomes and Metabolic AMPK-ULK1-ATG7 Pathways

TGF-β通过触发mTORC1(弱)介导的转录FOXO1-TCF1-Eomes通路和代谢AMPK-ULK1-ATG7通路激活来调节CD8(+) T细胞记忆

Wu, Zhaojia; Yu, Michelle; Leary, Scot C; Yuan, Jianbo; Huang, Junqiong; Xiang, Jim

The 41BB-agonist potentiates the therapeutic efficacy of a combined irreversible electroporation ablation treatment of lung cancer by promoting unexpected CD8(+)CD103(+) cDC1 and tissue-resident memory T cell responses

41BB激动剂通过促进意想不到的CD8(+)CD103(+) cDC1和组织驻留记忆T细胞反应,增强了肺癌联合不可逆电穿孔消融治疗的疗效。

Fang, Chen; Wu, Zhaojia; Leary, Scot C; Bai, Yiling; Yu, Michelle; Baniak, Nicolas; Ahmed, Shahid; Groot, Gary; Moser, Michael; Zhang, Wenjun; Zhang, Bing; Huang, Junqiong; Ma, Haitao; Feng, Yu; Xiang, Jim

CD40 agonist improves the therapeutic efficacy of irreversible electroporation ablation for metastatic melanoma by promoting unexpected CD8(+)CD103(+) cDC1 and TRM cell responses

CD40激动剂通过促进意想不到的CD8(+)CD103(+) cDC1和TRM细胞反应,提高了不可逆电穿孔消融治疗转移性黑色素瘤的疗效。

Wu, Zhaojia; Yang, Zhenyu; Iftikhar, Tauqeer; Groot, Gary; Leary, Scot C; Baniak, Nicolas; Ahmed, Shahid; Bosch, Mark; Moser, Michael; Zhang, Wenjun; Jiang, Junhong; Xiang, Jim

Molecular basis and pathways of the Yin-Yang theory in T cell immunity

T细胞免疫中阴阳理论的分子基础和途径

Xiang, Jim; Leary, Scot C; Wu, Zhaojia; Yu, Michelle

Author Correction: Distinct strengths of mTORC1 control T-cell memory via transcriptional FOXO1 and metabolic AMPKα1 pathways in linear cell differentiation and asymmetric cell division models

作者更正:mTORC1 通过转录 FOXO1 和代谢 AMPKα1 通路在线性细胞分化和不对称细胞分裂模型中对 T 细胞记忆的不同调控作用

Huang, Junqiong; Leary, Scot; Xiang, Jim

Distinct strengths of mTORC1 control T-cell memory via transcriptional FOXO1 and metabolic AMPKα1 pathways in linear cell differentiation and asymmetric cell division models

mTORC1通过转录FOXO1和代谢AMPKα1通路在线性细胞分化和不对称细胞分裂模型中对T细胞记忆的不同调控作用

Huang, Junqiong; Leary, Scot; Xiang, Jim

Aptamers, the Nucleic Acid Antibodies, in Cancer Therapy

适体,即核酸抗体,在癌症治疗中的应用

Fu, Zhaoying; Xiang, Jim

Aptamer-Functionalized Nanoparticles in Targeted Delivery and Cancer Therapy

适体功能化纳米粒子在靶向递送和癌症治疗中的应用

Fu, Zhaoying; Xiang, Jim

TLR9 agonist enhances radiofrequency ablation-induced CTL responses, leading to the potent inhibition of primary tumor growth and lung metastasis

TLR9激动剂可增强射频消融诱导的CTL反应,从而有效抑制原发肿瘤生长和肺转移。

Xu, Aizhang; Zhang, Lifeng; Yuan, Jingying; Babikr, Fatma; Freywald, Andrew; Chibbar, Rajni; Moser, Michael; Zhang, Wenjun; Zhang, Bing; Fu, Zhaoying; Xiang, Jim

Mannose-6-phosphate receptor: a novel regulator of T cell immunity

甘露糖-6-磷酸受体:T细胞免疫的新型调节因子

Ara, Anjuman; Ahmed, Khawaja Ashfaque; Xiang, Jim