日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Overexpression of mGlu(7B) in Mice: Implications for Neurodevelopmental Disorders.

小鼠中 mGlu(7B) 的过度表达：对神经发育障碍的影响。

期刊:Molecular Neurobiology
影响因子:4.3
doi:10.1007/s12035-025-05183-y
Freitas Geanne A, Weiss Kelly, Bavadekar Vaishnavi, Vermudez Sheryl Anne D, Fisher Nicole M, Buch Aditi, Dogra Shalini, Xiang Zixiu, Gogliotti Rocco G, Niswender Colleen M
神经科学
发表日期：2025
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Application of Deuterium in an M(1) Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422

氘在M(1)正变构调节剂备用方案中的应用：VU6045422的发现

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.5c00119
Engers, Julie L; Li, Jinming; Han, Changho; Long, Madeline F; Gregro, Alison R; Presley, Christopher C; Dickerson, Jonathan W; Peng, Weimin; Cho, Hyekyung P; Rodriguez, Alice L; Xiang, Zixiu; Boutaud, Olivier; O'Carroll, Colin; Dey, P Markus; Burstein, Ethan S; Niswender, Colleen M; Rook, Jerri M; Conn, P Jeffrey; Engers, Darren W; Lindsley, Craig W
发表日期：2025
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Profiling the Impact of mGlu(7)/Elfn1 Protein Interactions on the Pharmacology of mGlu(7) Allosteric Modulators

分析mGlu(7)/Elfn1蛋白相互作用对mGlu(7)变构调节剂药理学的影响

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.5c00174
Lei, Xia; Xiang, Zixiu; Rodriguez, Alice L; Wilson, Margaret L; Niswender, Colleen M
发表日期：2025
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Activation of Metabotropic Glutamate Receptor 3 Modulates Thalamo-accumbal Transmission and Rescues Schizophrenia-Like Physiological and Behavioral Deficits.

代谢型谷氨酸受体 3 的激活调节丘脑-伏隔核传递，并挽救精神分裂症样生理和行为缺陷

期刊:Biological Psychiatry
影响因子:9
doi:10.1016/j.biopsych.2023.11.023
Dogra Shalini, Aguayo Caleb, Xiang Zixiu, Putnam Jason, Smith Joshua, Johnston Curran, Foster Daniel J, Lindsley Craig W, Niswender Colleen M, Conn P Jeffrey
代谢
发表日期：2024
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Discovery of VU6007496: Challenges in the Development of an M(1) Positive Allosteric Modulator Backup Candidate

VU6007496 的发现：M(1) 正变构调节剂备选候选药物开发中的挑战

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.4c00508
Engers, Julie L; Bollinger, Katrina A; Capstick, Rory A; Long, Madeline F; Bender, Aaron M; Dickerson, Jonathan W; Peng, Weimin; Presley, Christopher C; Cho, Hyekyung P; Rodriguez, Alice L; Niswender, Colleen M; Moran, Sean P; Xiang, Zixiu; Blobaum, Anna L; Boutaud, Olivier; Rook, Jerri M; Engers, Darren W; Conn, P Jeffrey; Lindsley, Craig W
发表日期：2024
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Acute restraint stress redirects prefrontal cortex circuit function through mGlu(5) receptor plasticity on somatostatin-expressing interneurons

急性束缚应激通过生长抑素表达中间神经元上的mGlu(5)受体可塑性改变前额叶皮层回路功能

期刊:Neuron
影响因子:15
doi:10.1016/j.neuron.2021.12.027
Joffe, Max E; Maksymetz, James; Luschinger, Joseph R; Dogra, Shalini; Ferranti, Anthony S; Luessen, Deborah J; Gallinger, Isabel M; Xiang, Zixiu; Branthwaite, Hannah; Melugin, Patrick R; Williford, Kellie M; Centanni, Samuel W; Shields, Brenda C; Lindsley, Craig W; Calipari, Erin S; Siciliano, Cody A; Niswender, Colleen M; Tadross, Michael R; Winder, Danny G; Conn, P Jeffrey
信号转导
神经科学
发表日期：2022
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Differential activity of mGlu(7) allosteric modulators provides evidence for mGlu(7/8) heterodimers at hippocampal Schaffer collateral-CA1 synapses

mGlu(7)变构调节剂的差异活性为海马Schaffer侧支-CA1突触处mGlu(7/8)异二聚体的存在提供了证据。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1016/j.jbc.2022.102458
Lin, Xin; Fisher, Nicole M; Dogra, Shalini; Senter, Rebecca K; Reed, Carson W; Kalbfleisch, Jacob J; Lindsley, Craig W; Asher, Wesley B; Xiang, Zixiu; Niswender, Colleen M; Javitch, Jonathan A
神经科学
发表日期：2022
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Ultrasound neuromodulation depends on pulse repetition frequency and can modulate inhibitory effects of TTX

超声神经调控取决于脉冲重复频率，并且可以调节TTX的抑制作用。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-020-72189-y
Manuel, Thomas J; Kusunose, Jiro; Zhan, Xiaoyan; Lv, Xiaohui; Kang, Ellison; Yang, Aaron; Xiang, Zixiu; Caskey, Charles F
信号转导
发表日期：2020
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M(1)-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition

缺乏激动剂活性的M(1)正向变构调节剂是增强认知能力的最佳选择。

期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/s41386-018-0033-9
Moran, Sean P; Dickerson, Jonathan W; Cho, Hyekyung P; Xiang, Zixiu; Maksymetz, James; Remke, Daniel H; Lv, Xiaohui; Doyle, Catherine A; Rajan, Deepa H; Niswender, Colleen M; Engers, Darren W; Lindsley, Craig W; Rook, Jerri M; Conn, P Jeffrey
神经科学
发表日期：2018
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Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M(4) Muscarinic Receptor

胆碱能投射至黑质网状部，通过M(4)毒蕈碱受体抑制多巴胺对基底神经节的调节

期刊:Neuron
影响因子:15
doi:10.1016/j.neuron.2017.12.008
Moehle, Mark S; Pancani, Tristano; Byun, Nellie; Yohn, Samantha E; Wilson, George H 3rd; Dickerson, Johnathan W; Remke, Daniel H; Xiang, Zixiu; Niswender, Colleen M; Wess, Jürgen; Jones, Carrie K; Lindsley, Craig W; Rook, Jerri M; Conn, P Jeffrey
信号转导
发表日期：2017
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