日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Microglial CR3-mediated synaptic pruning in the dmPFC promotes the generation and maintenance of chronic muscle pain via glutamatergic dysfunction

背内侧前额叶皮层（dmPFC）中小胶质细胞CR3介导的突触修剪通过谷氨酸能功能障碍促进慢性肌肉疼痛的产生和维持。

期刊:Experimental and Molecular Medicine
影响因子:12.9
doi:10.1038/s12276-026-01666-7
Luo, Meiling; Wang, Likai; Liang, Yanan; Xu, Qianxi; Zhang, Siqi; Xing, Xiangxin; Niu, Shuangyang; Wang, Yonghui
胶质细胞
细胞生物学
神经科学
发表日期：2026
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Paroxetine repurposing enhances antitumor immunity via SPOP-mediated PD-L1 ubiquitination and proteasomal degradation

帕罗西汀的重新定位通过SPOP介导的PD-L1泛素化和蛋白酶体降解增强抗肿瘤免疫力。

期刊:Journal of Experimental & Clinical Cancer Research
影响因子:12.8
doi:10.1186/s13046-026-03648-z
Xu, Mengting; Tian, Saisai; Xu, Hanchi; Xue, Xinying; Zhang, Qing; Hu, Hongmei; Wu, Gaosong; Geng, Xiangxin; Yu, Dianping; Xu, Hanchen; Xie, Mei; Li, Linyang; Li, Xinru; Li, Simeng; Xie, Shize; Lin, Xuwen; Lyu, Shuzhen; Xie, Yutong; Zhang, Biao; Zhou, Haiyang; Wang, Qun; Zhang, Weidong; Liu, Sanhong
肿瘤
表观遗传
肿瘤免疫
泛素化
SPOP
PD-L1
免疫/内分泌
发表日期：2026
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BMP6 as a therapeutic target for preeclampsia: enhancing trophoblast invasion and vascular mimicry.

BMP6 作为先兆子痫的治疗靶点：增强滋养层细胞侵袭和血管拟态。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-06040-w
Niu Yue, Han Shuwen, Xiao Huiying, Liu Mingxi, Yu Yunhai, Klein Cameron, Lan Xiangxin, Li Yan, Yuan Haitao, Zhang Ping, Wei Daimin
细胞生物学
发表日期：2026
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Distinguishing nontuberculous mycobacterial lung disease from pulmonary tuberculosis using radiomics machine learning models from CT images

利用放射组学机器学习模型从CT图像中区分非结核分枝杆菌肺病和肺结核

期刊:Frontiers in Medicine
影响因子:3
doi:10.3389/fmed.2026.1721949
Zheng, Jiaofeng; Wang, Fang; Zeng, Xiangxin; Shu, Weiqiang; He, Zhiyang; Li, Yurui; Gao, Yueqin; Lv, Shengxiu; Liu, Xueyan
微生物学
肺结核
发表日期：2026
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Acevaltrate as a novel ferroptosis inducer with dual targets of PCBP1/2 and GPX4 in colorectal cancer

乙酰伐特作为一种新型铁死亡诱导剂，在结直肠癌中具有PCBP1/2和GPX4双重靶点作用。

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02296-7
Yu, Dianping; Hu, Hongmei; Zhang, Qing; Wang, Chengji; Xu, Mengting; Xu, Hanchen; Geng, Xiangxin; Cai, Minchen; Zhang, Hongwei; Guo, Mengmeng; Lu, Dong; Xu, Hanchi; Li, Linyang; Zhang, Xing; Shen, Ruling; Lin, Sheng; Wang, Qun; Zhang, Weidong; Liu, Sanhong
肿瘤
肠癌
肿瘤免疫
CBP
铁死亡
GPX4
发表日期：2025
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Marine Natural Product Chagosendine C Induces Cuproptosis in Colorectal Cancer Cells by Targeting FDX1

海洋天然产物查戈森定C通过靶向FDX1诱导结直肠癌细胞凋亡

期刊:Journal of the American Chemical Society
影响因子:15.6
doi:10.1021/jacs.5c07917
Tao, Xiaoyu; Wang, Hongru; Wang, Qun; Wang, Chengji; Shao, Chang-Wei; Jin, Yang; Yu, Dianping; Hu, Hongmei; Zhang, Qing; Xu, Mengting; Geng, Xiangxin; Xu, Hanchi; Li, Linyang; Shen, Ruling; Guo, Yue-Wei; Li, Xu-Wen; Liu, Sanhong; Zhang, Weidong
肿瘤
肠癌
表观遗传
肿瘤免疫
凋亡
细胞生物学
发表日期：2025
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Network Medicine-Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD-L1 Expression via Targeting SPOP in Cancer

基于网络医学的策略发现，马普替林可通过靶向SPOP抑制PD-L1表达，从而成为一种可重新利用的药物。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202410285
Tian, Saisai; Xu, Mengting; Geng, Xiangxin; Fang, Jiansong; Xu, Hanchen; Xue, Xinying; Hu, Hongmei; Zhang, Qing; Yu, Dianping; Guo, Mengmeng; Zhang, Hongwei; Lu, Jinyuan; Guo, Chengyang; Wang, Qun; Liu, Sanhong; Zhang, Weidong
PD-L1
SPOP
发表日期：2025
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Targeting granulosa cells with engineered DFO nanoparticles for the treatment of chemotherapy-induced premature ovarian failure.

利用工程化DFO纳米颗粒靶向颗粒细胞治疗化疗引起的卵巢早衰

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.115416
Zhang Tuo, Sheng Zhiyi, Zhang Jixian, Zhang Heng, Zhang Yan, Du Yunpeng, Liu Xiangxin, Hu Zhu, Luo Qiyuan, Xu Guoqiang, Gao Yuan, He Meina, Chen Tengxiang
细胞生物学
细胞基因治疗
发表日期：2025
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Cordycepin Targets HRD1 to Promote Cancer Cell PD-L1 Ubiquitin-Proteasome Degradation and Increase Antitumor Immunity

虫草素靶向HRD1促进癌细胞PD-L1泛素-蛋白酶体降解并增强抗肿瘤免疫力

期刊:MedComm
影响因子:10.7
doi:10.1002/mco2.70430
Geng, Xiangxin; Cai, Minchen; Hu, Hongmei; Xu, Mengting; Zhang, Qing; Xu, Hanchen; Yu, Dianping; Zhang, Hongwei; Xu, Hanchi; Li, Linyang; Guo, Mengmeng; Xie, Shize; Wang, Qun; Zhang, Weidong; Liu, Sanhong
肿瘤
肿瘤免疫
PD-L1
细胞生物学
免疫/内分泌
发表日期：2025
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SIRT2 Inhibition promotes microglia LC3-associated phagocytosis via NRF2/CD36 after the experimental subarachnoid hemorrhage.

SIRT2 抑制可促进实验性蛛网膜下腔出血后小胶质细胞通过 NRF2/CD36 进行 LC3 相关吞噬作用。

期刊:Journal of Neuroinflammation
影响因子:10.1
doi:10.1186/s12974-025-03623-z
Sheng Bin, Chen Xiangxin, Tao Tao, Sun Jiaqing, Li Wei, Wu Lingyun, Peng Zheng, Li Xiaojian, Zhou Zhengxu, Yu Qian, Ling Yeping, Sherchan Prativa, Flores Jerry J, Tang Jiping, Huang Lei, Hang Chunhua, Zhang John H
细胞生物学
胶质细胞
CD3
CD36
NRF2
SirT2
发表日期：2025
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