日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Automatically Defining Protein Words for Diverse Functional Predictions Based on Attention Analysis of a Protein Language Model

基于蛋白质语言模型注意力分析的蛋白质词汇自动定义及其在多种功能预测中的应用

Chen, Hedi; Zhong, Jingrui; Zhang, Xiaochun; Chen, Jingke; Guo, Lin; Xiong, Xiaoliang; Zhang, Xiaonan; Liu, Xiangyu; Xiao, Bailong; Tian, Boxue

The fetal hydrops-associated single-residue mutation L322P disrupts mechanical but not chemical activation of the PIEZO1 ion channel.

与胎儿水肿相关的单残基突变 L322P 会破坏 PIEZO1 离子通道的机械激活,但不会破坏其化学激活

Jiang Jinghui, Guo Wei, Chen Xudong, He Qijing, Wang Yubo, Zhu Xiaohui, Yan Liying, Qiao Jie, Xiao Bailong

The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction

机械敏感性Piezo1通道介导心脏机械-化学信号转导。

Jiang, Fan; Yin, Kunlun; Wu, Kun; Zhang, Mingmin; Wang, Shiqiang; Cheng, Heping; Zhou, Zhou; Xiao, Bailong

STIM1 thermosensitivity defines the optimal preference temperature for warm sensation in mice

STIM1 热敏性决定了小鼠对温暖感觉的最佳偏好温度。

Liu, Xiaoling; Wang, Haiping; Jiang, Yan; Zheng, Qin; Petrus, Matt; Zhang, Mingmin; Zheng, Sisi; Schmedt, Christian; Dong, Xinzhong; Xiao, Bailong

The mechanosensitive Piezo1 channel: structural features and molecular bases underlying its ion permeation and mechanotransduction

机械敏感性Piezo1通道:其离子渗透和机械转导的结构特征和分子基础。

Wang, Yubo; Xiao, Bailong

Visualizing Human Embryonic Development of the Heart’s Outflow Tract

可视化人类胚胎心脏流出道发育过程

Xiao, Bailong; Zhong, Guofeng; Obayashi, Masakazu; Yang, Dongmei; Chen, Keyun; Walsh, Michael P; Shimoni, Yakhin; Cheng, Heping; Ter Keurs, Henk; Chen, S R Wayne; Sidorowych, Christina; Lebowicz, Leah; Daugherty, John; Brennan, Kevin; Bond, Sam; Ross, Callum; Cotanche, Douglas

Piezo proteins are pore-forming subunits of mechanically activated channels

压电蛋白是机械激活通道的孔形成亚基。

Coste, Bertrand; Xiao, Bailong; Santos, Jose S; Syeda, Ruhma; Grandl, Jörg; Spencer, Kathryn S; Kim, Sung Eun; Schmidt, Manuela; Mathur, Jayanti; Dubin, Adrienne E; Montal, Mauricio; Patapoutian, Ardem

Temperature-dependent STIM1 activation induces Ca²+ influx and modulates gene expression

温度依赖性的STIM1激活诱导Ca²⁺内流并调节基因表达

Xiao, Bailong; Coste, Bertrand; Mathur, Jayanti; Patapoutian, Ardem

Localization of PKA phosphorylation site, Ser(2030), in the three-dimensional structure of cardiac ryanodine receptor

PKA磷酸化位点Ser(2030)在心脏兰尼碱受体三维结构中的定位

Jones, Peter P; Meng, Xing; Xiao, Bailong; Cai, Shitian; Bolstad, Jeff; Wagenknecht, Terence; Liu, Zheng; Chen, S R Wayne