日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of novel BCAT2 inhibitors: design, synthesis, in vitro evaluation, and molecular modeling studies

新型BCAT2抑制剂的发现：设计、合成、体外评价和分子建模研究

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d6md00019c
Xu, Dong; Weng, Wenxiu; Cao, Huining; Zhang, Chao; Zhang, Yudi; Li, Yan; Xiao, Junhai; Xie, Hua; Guo, Jialin; Chen, Guoliang
发表日期：2026
文献求助 收藏

Novel Quaternary Ammonium Salt-Linked STING Agonist Antibody-Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off-Target Toxicity.

新型季铵盐连接的 STING 激动剂抗体-药物偶联物：协同激活肿瘤免疫并减轻脱靶毒性

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202502270
Long Yu, Tang Borui, Xie Fei, Liu Lianqi, Zhou Yangyihua, Dong Jingwen, Wang Jianfeng, Sun Cuicui, Wang Yuting, Li Ruoqi, Zhang Na, Li Liping, Luo Longlong, Xiao Junhai, Zhong Wu, Xiao Dian, Deng Hongbin, Zhou Xinbo
肿瘤
肿瘤免疫
发表日期：2025
文献求助 收藏

A Bifunctional SARS-CoV-2 Entry Inhibitor Targeting the Host Protease TMPRSS2 and Viral Spike Protein HR1 Region

一种靶向宿主蛋白酶TMPRSS2和病毒刺突蛋白HR1区域的双功能SARS-CoV-2入侵抑制剂

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms26178289
Wang, Huan; Li, Qing; Yin, Zhe; Du, Shu; Zheng, Longbo; Du, Xinmeng; Shi, Anqi; Li, Jichun; Shi, Weiguo; Yu, Fei; Xiao, Junhai; Wang, Chao
微生物学
SARS-CoV-2
发表日期：2025
文献求助 收藏

Comprehensive Identification and Mechanistic Evaluation of Novel DHODH Inhibitors as Potent Broad-Spectrum Antiviral Agents

新型DHODH抑制剂作为强效广谱抗病毒药物的全面鉴定和机制评价

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph18091416
Zhang, Chao; Sun, Shiyang; Xie, Huiru; Ding, Yongzhao; Hu, Chun; Guo, Jialin; Xiao, Junhai
微生物学
DHODH
发表日期：2025
文献求助 收藏

Computational Discovery of Potent Nucleoprotein Inhibitors for Influenza A Virus: Validation Through QM/MM Analysis and Experimental Binding Assays

利用计算方法发现甲型流感病毒强效核蛋白抑制剂：通过QM/MM分析和实验结合试验进行验证

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30193960
Liu, Zixiao; Guo, Jialin; Zhang, Chao; Ding, Yongzhao; Sun, Shiyang; Yao, Binrong; Xing, Cheng; Liu, Xiaoping; Hu, Chun; Xiao, Junhai
微生物学
流感
多发性骨髓瘤
发表日期：2025
文献求助 收藏

Targeting clathrin-mediated endocytosis: recent advances in inhibitor development, mechanistic insights, and therapeutic prospects

靶向网格蛋白介导的内吞作用：抑制剂开发、机制研究及治疗前景的最新进展

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d5md00650c
Zhang, Chao; Guo, Jialin; Liu, Zixiao; Huang, Xuhui; Dong, Shiqi; Hu, Chun; Xiao, Junhai
发表日期：2025
文献求助 收藏

Design, Synthesis, and Biological Evaluation of the Quorum-Sensing Inhibitors of Pseudomonas aeruginosa PAO1

铜绿假单胞菌PAO1群体感应抑制剂的设计、合成及生物学评价

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules29102211
Yan, Xinlin; Hou, Shi; Xing, Cheng; Zhang, Yuanyuan; Chang, Jiajia; Xiao, Junhai; Lin, Feng
发表日期：2024
文献求助 收藏

Design, Synthesis, Bioactivity Evaluation, Crystal Structures, and In Silico Studies of New α-Amino Amide Derivatives as Potential Histone Deacetylase 6 Inhibitors

新型α-氨基酰胺衍生物作为潜在的组蛋白去乙酰化酶6抑制剂的设计、合成、生物活性评价、晶体结构和计算机模拟研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27103335
Xu, Yangrong; Tang, Hangjun; Xu, Yijie; Guo, Jialin; Zhao, Xu; Meng, Qingguo; Xiao, Junhai
乙酰化
表观遗传
发表日期：2022
文献求助 收藏

Nanomicrobiology

纳米微生物学

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms21061922
Pan, Xingquan; Xie, Fei; Xiao, Dian; Zhou, Xinbo; Xiao, Junhai; Jain, Kewal K
微生物学
发表日期：2012
文献求助 收藏