文献库，生知库 | 链接生命科学的每一步

Huang Yue, Xiao Peifang, Qin Lei, Gao Li, Zhao Yang, Sui Jingru, Hu Wenting, Zhou Lei, Han Nan, Lv Xuan, Chen Kunying, Liu Yu, Lin Hanhong, Shen Shuhong, Abdel-Wahab Omar, Hu Shaoyan, Liu Zhaoqi, Wang Qianfei

白血病

治疗耐药

发表日期：2026

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Venetoclax combined with escalating doses of homoharringtonine, low-dose cytarabine, and granulocyte colony-stimulating factor demonstrates feasibility and tolerability for remission induction in pediatric acute myeloid leukemia

维奈托克联合递增剂量的同型三尖杉酯碱、低剂量阿糖胞苷和粒细胞集落刺激因子，在儿童急性髓系白血病的缓解诱导治疗中显示出可行性和耐受性。

期刊:Haematologica

影响因子:7.9

doi:10.3324/haematol.2024.286832

Cheng, Shengqin; Gao, Li; Lu, Jun; Hu, Yixin; Wang, Yi; He, Hailong; Li, Jie; Liu, Suxiang; Yang, Feiyun; Wu, Xiaofang; Fan, Liyan; Fan, Junjie; Yao, Yanhua; Sun, Yina; Li, Bohan; Zhang, Yongping; Wu, Shuiyan; Cheng, Cheng; Xiao, Peifang; Ribeiro, Raul C; Shaoyan, Hu

The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8.

RBM39 降解剂 indisulam 通过改变 ZMYND8 的选择性剪接来抑制急性巨核细胞白血病

期刊:Cell and Bioscience

影响因子:6.2

doi:10.1186/s13578-025-01380-3

Yang Ying, Li Zhiheng, Yang Yang, Xiao Peifang, He Zhixu, Zhang Zimu, Li Yizhen, Shi Lei, Wang Xiaodong, Tao Yanfang, Fan Junjie, Zhang Fenli, Yang Chunxia, Yao Fahua, Ji Tongting, Zhang Yongping, Zhou Bi, Yu Juanjuan, Guo Ailian, Wei Zhongling, Jiao Wanyan, Wu Yumeng, Li Yan, Wu Di, Wu Yijun, Gao Li, Hu Yixin, Pan Jian, Hu Shaoyan, Yang Xiaoyan

细胞生物学

发表日期：2025

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Impact of cyclosporine A-related single nucleotide polymorphisms on post-transplant outcomes in pediatric hematologic malignancy patients undergoing allogeneic hematopoietic stem cell transplantation

环孢素A相关单核苷酸多态性对接受异基因造血干细胞移植的儿童血液系统恶性肿瘤患者移植后结局的影响

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2025.1615976

Ji, Qi; Zhang, Senlin; Liu, Minyuan; Zhang, Weiliang; Liu, Lixia; Chai, Yutan; Gao, Li; Li, Bohan; Du, Zhizhuo; Hu, Yixin; Xiao, Peifang; Ling, Jing; Fan, Liyan; Bian, Xinni; Chen, Hong; Li, Jie; Lu, Jun; Zhang, Yongping; Wu, Shuiyan; Qin, Jiayue; Hu, Shaoyan; Li, Yizhen

A Multicenter Study of Acute Abdomen in Children With Acute Lymphoblastic Leukemia: CCCG-ALL-2015

儿童急性淋巴细胞白血病急性腹痛的多中心研究：CCCG-ALL-2015

期刊:Cancer Medicine

影响因子:3.1

doi:10.1002/cam4.71090

Gan, Wenting; Zhang, Weina; Cai, Jiaoyang; Zhu, Xiaofan; Yu, Jie; Xiao, Peifang; Gao, Ju; Fang, Yongjun; Liang, Changda; Li, Xue; Zhou, Fen; Zhai, Xiaowen; Xu, Xiaoxiao; Tian, Xin; Liu, Aiguo; Wang, Ningling; Zhu, Jiashi; Cheng, Frankie Wai-Tsoi; Yang, Liangchun; Zhang, Ge; Shen, Shuhong; Jiang, Hua; Wang, Lingzhen

Frequent TCR rearrangements in pediatric B-cell lymphoblastic acute leukemia: genomic and phenotypic features.

儿童B细胞淋巴母细胞急性白血病中频繁的TCR重排：基因组和表型特征。

期刊:Annals of Hematology

影响因子:2.4

doi:10.1007/s00277-025-06687-2

Zheng Jiajia, Wang Yiting, Li Zhiheng, Xiao Peifang, Lu Jun, Liu Hu, Hu Yixin, Wu Shuiyan, Li Bohan, Gao Li, Ji Qi, He Hailong, Wang Yi, Li Jie, Chen Nan, Meng Lijun, Tian Yuanyuan, Li Yizhen, Xiao Sheng, Hu Shaoyan

Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China

CD9在儿童急性淋巴细胞白血病预后中的意义：来自中国一项全国多中心研究的启示

期刊:Leukemia

影响因子:13.4

doi:10.1038/s41375-023-02089-3

Leung, Kam Tong; Cai, Jiaoyang; Liu, Yu; Chan, Kathy Yuen Yee; Shao, Jingbo; Yang, Hui; Hu, Qun; Xue, Yao; Wu, Xuedong; Guo, Xia; Zhai, Xiaowen; Wang, Ningling; Li, Xue; Tian, Xin; Li, Zheng; Xue, Ning; Guo, Yuxia; Wang, Lingzhen; Zou, Yao; Xiao, Peifang; He, Yingyi; Jin, Runming; Tang, Jingyan; Yang, Jun J; Shen, Shuhong; Pui, Ching-Hon; Li, Chi Kong

A multicenter retrospective comparison between systemic mastocytosis with t(8;21) AML and KIT mutant t(8;21) AML

系统性肥大细胞增多症合并t(8;21) AML和KIT突变型t(8;21) AML的多中心回顾性比较

期刊:Blood Advances

影响因子:7.1

doi:10.1182/bloodadvances.2023012006

Zhang, Zhibo; Yin, Jia; Lian, Guoli; Bao, Xiebing; Hu, Meng; Liu, Zhenfang; Yu, Yuan; Mi, Ruihua; Zuo, Yabei; Shi, Pengcheng; Zheng, Weiyan; Jiang, Qian; Chao, Hongying; Xiao, Peifang; Yu, Weijuan; Han, Yanqiu; Wu, Yu; Zeng, Yan; Wu, Depei; Yang, Xiaofei; Chen, Suning

Infectious complications in pediatric patients undergoing CD19+CD22+ chimeric antigen receptor T-cell therapy for relapsed/refractory B-lymphoblastic leukemia

接受 CD19+CD22+ 嵌合抗原受体 T 细胞疗法治疗复发/难治性 B 淋巴母细胞白血病的儿科患者的感染并发症

期刊:Clinical and Experimental Medicine

影响因子:3.5

doi:10.1007/s10238-024-01339-7

Wu, Xiaochen; Cao, Zhanmeng; Chen, Zihan; Wang, Yi; He, Hailong; Xiao, Peifang; Hu, Shaoyan; Lu, Jun; Li, Benshang

Post-transplant complications revealed by mycophenolate mofetil related transporters and metabolic enzymes gene polymorphisms in pediatric patients with hematological disorders

移植后并发症与儿科血液病患者中吗替麦考酚酯相关转运蛋白和代谢酶基因多态性的关系

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-024-13227-0

Ji, Qi; Hu, Yixin; Liu, Minyuan; Liu, Lixia; Zheng, Jiajia; Du, Zhizhuo; Gao, Li; Xiao, Peifang; Ling, Jing; Fan, Liyan; Bian, Xinni; Lou, Feng; Cao, Shanbo; Li, Jie; Tian, Yuanyuan; Lu, Jun; Qin, Jiayue; Hu, Shaoyan

代谢

发表日期：2024

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Sequence-dependent splicing dysregulation drives therapy resistance in pediatric AML.

序列依赖性剪接失调是儿童急性髓系白血病治疗耐药性的主要原因。

Venetoclax combined with escalating doses of homoharringtonine, low-dose cytarabine, and granulocyte colony-stimulating factor demonstrates feasibility and tolerability for remission induction in pediatric acute myeloid leukemia

维奈托克联合递增剂量的同型三尖杉酯碱、低剂量阿糖胞苷和粒细胞集落刺激因子，在儿童急性髓系白血病的缓解诱导治疗中显示出可行性和耐受性。

The RBM39 degrader indisulam inhibits acute megakaryoblastic leukemia by altering the alternative splicing of ZMYND8.

RBM39 降解剂 indisulam 通过改变 ZMYND8 的选择性剪接来抑制急性巨核细胞白血病

Impact of cyclosporine A-related single nucleotide polymorphisms on post-transplant outcomes in pediatric hematologic malignancy patients undergoing allogeneic hematopoietic stem cell transplantation

环孢素A相关单核苷酸多态性对接受异基因造血干细胞移植的儿童血液系统恶性肿瘤患者移植后结局的影响

A Multicenter Study of Acute Abdomen in Children With Acute Lymphoblastic Leukemia: CCCG-ALL-2015

儿童急性淋巴细胞白血病急性腹痛的多中心研究：CCCG-ALL-2015

Frequent TCR rearrangements in pediatric B-cell lymphoblastic acute leukemia: genomic and phenotypic features.

儿童B细胞淋巴母细胞急性白血病中频繁的TCR重排：基因组和表型特征。

Prognostic implications of CD9 in childhood acute lymphoblastic leukemia: insights from a nationwide multicenter study in China

CD9在儿童急性淋巴细胞白血病预后中的意义：来自中国一项全国多中心研究的启示

A multicenter retrospective comparison between systemic mastocytosis with t(8;21) AML and KIT mutant t(8;21) AML

系统性肥大细胞增多症合并t(8;21) AML和KIT突变型t(8;21) AML的多中心回顾性比较

Infectious complications in pediatric patients undergoing CD19+CD22+ chimeric antigen receptor T-cell therapy for relapsed/refractory B-lymphoblastic leukemia

接受 CD19+CD22+ 嵌合抗原受体 T 细胞疗法治疗复发/难治性 B 淋巴母细胞白血病的儿科患者的感染并发症

Post-transplant complications revealed by mycophenolate mofetil related transporters and metabolic enzymes gene polymorphisms in pediatric patients with hematological disorders

移植后并发症与儿科血液病患者中吗替麦考酚酯相关转运蛋白和代谢酶基因多态性的关系