日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Direct lysine dimethylation of IRF3 by the methyltransferase SMYD3 attenuates antiviral innate immunity

甲基转移酶SMYD3对IRF3的赖氨酸直接二甲基化可减弱抗病毒先天免疫反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2320644122
Wang, Zixuan; Chen, Xiaoyun; Zhu, Chunchun; Fan, Sijia; Tang, Jinhua; Deng, Hongyan; Sun, Xueyi; Liu, Xing; Xiao, Wuhan
IRF3
SMYD3
表观遗传
微生物学
免疫/内分泌
发表日期：2025
文献求助 收藏

MYLIP attenuates hypoxia tolerance by inducing K27-linked polyubiquitination and subsequent proteasomal degradation of HIF-α.

MYLIP 通过诱导 K27 连接的多聚泛素化和随后的 HIF-α 蛋白酶体降解来减弱缺氧耐受性

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08200-x
Li Jun, Li Zhi, Li Xiong, Li Ziyi, Song Yanan, Yuan Le, Wang Yanyi, Yan Runkun, Lai Fuxiang, Wang Jing, Xiao Wuhan
表观遗传
泛素化
发表日期：2025
文献求助 收藏

Dual modifying of MAVS at lysine 7 by SIRT3-catalyzed deacetylation and SIRT5-catalyzed desuccinylation orchestrates antiviral innate immunity

MAVS蛋白第7位赖氨酸的双重修饰，即SIRT3催化的脱乙酰化和SIRT5催化的脱琥珀酰化，协调抗病毒先天免疫反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2314201121
Liu, Xing; Zhu, Chunchun; Jia, Shuke; Deng, Hongyan; Tang, Jinhua; Sun, Xueyi; Zeng, Xiaoli; Chen, Xiaoyun; Wang, Zixuan; Liu, Wen; Liao, Qian; Zha, Huangyuan; Cai, Xiaolian; Xiao, Wuhan
表观遗传
琥珀酰化
微生物学
MAVS
乙酰化
免疫/内分泌
发表日期：2024
文献求助 收藏

Zebrafish phd1 enhances mavs-mediated antiviral responses in a hydroxylation-independent manner.

斑马鱼 phd1 以不依赖于羟基化的方式增强 mavs 介导的抗病毒反应

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.01038-24
Yu Guangqing, Yuan Le, Li Xiong, Zuo Mingzhong, Wang Rui, Chen Mengjuan, Liu Yuqing, Liu Xing, Xiao Wuhan
Fish
Viral
viral
发表日期：2024
文献求助 收藏

Author Correction: ELL targets c-Myc for proteasomal degradation and suppresses tumour growth

作者更正：ELL靶向c-Myc进行蛋白酶体降解并抑制肿瘤生长

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-023-38151-y
Chen, Yu; Zhou, Chi; Ji, Wei; Mei, Zhichao; Hu, Bo; Zhang, Wei; Zhang, Dawei; Wang, Jing; Liu, Xing; Ouyang, Gang; Zhou, Jiangang; Xiao, Wuhan
肿瘤免疫
肿瘤
发表日期：2023
文献求助 收藏

Asymmetric arginine dimethylation of cytosolic RNA and DNA sensors by PRMT3 attenuates antiviral innate immunity

PRMT3介导的胞质RNA和DNA传感器的不对称精氨酸二甲基化作用会减弱抗病毒先天免疫反应。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2214956120
Zhu, Junji; Li, Xiong; Cai, Xiaolian; Zhou, Ziwen; Liao, Qian; Liu, Xing; Wang, Jing; Xiao, Wuhan
微生物学
表观遗传
免疫/内分泌
发表日期：2023
文献求助 收藏

Neddylation Facilitates the Antiviral Response in Zebrafish

NEDDylation 促进斑马鱼的抗病毒反应

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2019.01432
Yu, Guangqing; Liu, Xing; Tang, Jinhua; Xu, Chenxi; Ouyang, Gang; Xiao, Wuhan
微生物学
发表日期：2019
文献求助 收藏

PELP1 Suppression Inhibits Gastric Cancer Through Downregulation of c-Src-PI3K-ERK Pathway.

PELP1抑制通过下调c-Src-PI3K-ERK通路抑制胃癌

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2019.01423
Yan Hongzhu, Sun Yanling, Wu Qian, Wu Zhe, Hu Meichun, Sun Yuanpeng, Liu Yusi, Ma Zi, Liu Shangqin, Xiao Wuhan, Liu Fuxing, Ning Zhifeng
肿瘤
胃癌
发表日期：2019
文献求助 收藏

Deletion of the fih gene encoding an inhibitor of hypoxia-inducible factors increases hypoxia tolerance in zebrafish

斑马鱼中编码缺氧诱导因子抑制剂的fih基因缺失可提高其对缺氧的耐受性。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.RA118.003004
Cai, Xiaolian; Zhang, Dawei; Wang, Jing; Liu, Xing; Ouyang, Gang; Xiao, Wuhan
发表日期：2018
文献求助 收藏

Zebrafish androgen receptor is required for spermatogenesis and maintenance of ovarian function

斑马鱼雄激素受体是精子发生和维持卵巢功能所必需的。

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.24407
Yu, Guangqing; Zhang, Dawei; Liu, Wei; Wang, Jing; Liu, Xing; Zhou, Chi; Gui, Jianfang; Xiao, Wuhan
信号转导
免疫/内分泌
发表日期：2018
文献求助 收藏