The pronounced cytotoxic effects of chimeric antigen receptor T cells targeting B7-H3 in organoids and liver xenografts derived from colorectal cancer patients
嵌合抗原受体T细胞靶向B7-H3在结直肠癌患者来源的类器官和肝脏异种移植模型中表现出显著的细胞毒性作用
期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-025-03114-1
Sheng, Yuling; Yan, Li; Liu, Qi; Peng, Yifan; Tan, Jingyun; Li, Wenhua; Mao, Wei; Wei, Wenqing; Chang, Yanyun; Cao, Linlin; Tan, Yi; Xiao, Yanlin; Zhang, Wenyong; Gao, Jing; Xu, Yang; Du, Changzheng
肿瘤
肠癌
T细胞
肿瘤免疫
信号转导
T细胞
3D/类器官
细胞生物学
毒理研究
免疫/内分泌
