Imperatorin Alleviates Intestinal Fibrosis by Suppressing AIM2-mediated GSDMD Pyroptosis in Macrophages.
Imperatorin 通过抑制巨噬细胞中 AIM2 介导的 GSDMD 焦亡来缓解肠道纤维化。
期刊:Cellular and Molecular Gastroenterology and Hepatology
影响因子:7.4
doi:10.1016/j.jcmgh.2025.101625
Li Sheng, Zhu Fangqing, Xie Yao, Ben Teng, Liu Ke, Lin Xinlong, Zhou Qian, Zhang Yin, Zhang Xinyue, Chen Yeling, Ren Yuexin, Wang Xianfei, Zhi Fachao, Tan Gao
细胞生物学
巨噬细胞
DMD
AIM2
GSDMD
巨噬细胞
焦亡