GSDME promotes MASLD by regulating pyroptosis, Drp1 citrullination-dependent mitochondrial dynamic, and energy balance in intestine and liver.
GSDME 通过调节肠道和肝脏中的细胞焦亡、Drp1 瓜氨酸化依赖的线粒体动力学和能量平衡来促进 MASLD
期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-024-01343-0
Zhu Jia-Hui, Ouyang Shen-Xi, Zhang Guo-Yan, Cao Qi, Xin Rujuan, Yin Hang, Wu Jing-Wen, Zhang Yan, Zhang Zhen, Liu Yi, Fu Jiang-Tao, Chen Yi-Ting, Tong Jie, Zhang Jia-Bao, Liu Jian, Shen Fu-Ming, Li Dong-Jie, Wang Pei
