日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Therapeutic Potential of Baicalein in Endometrial Cancer: Suppression of mTOR Signaling and Synergy with Metformin

黄芩苷在子宫内膜癌中的治疗潜力:抑制mTOR信号通路及其与二甲双胍的协同作用

Dumitriu, Alison L; Wen, Wei; Yan, Jin; Xing, Quanhua; Ro, Finn E; Han, Ernest S; Yim, John H

Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells

黄芩苷上调DDIT4表达,从而介导mTOR抑制和癌细胞生长抑制。

Wang, Yujun; Han, Ernest; Xing, Quanhua; Yan, Jin; Arrington, Amanda; Wang, Charles; Tully, Dylan; Kowolik, Claudia M; Lu, David M; Frankel, Paul H; Zhai, Jing; Wen, Wei; Horne, David; Yip, M L Richard; Yim, John H

Interferon Regulatory Factor 1 (IRF-1) induces p21(WAF1/CIP1) dependent cell cycle arrest and p21(WAF1/CIP1) independent modulation of survivin in cancer cells

干扰素调节因子 1 (IRF-1) 诱导 p21(WAF1/CIP1) 依赖性细胞周期阻滞,并以 p21(WAF1/CIP1) 非依赖性方式调节癌细胞中的 survivin 表达。

Armstrong, Michaele J; Stang, Michael T; Liu, Ye; Gao, Jinbo; Ren, Baoguo; Zuckerbraun, Brian S; Mahidhara, Raja S; Xing, Quanhua; Pizzoferrato, Eva; Yim, John H

Identification of a natural compound by cell-based screening that enhances interferon regulatory factor-1 activity and causes tumor suppression.

通过基于细胞的筛选鉴定出一种天然化合物,该化合物可增强干扰素调节因子-1的活性并抑制肿瘤生长

Gao Jinbo, Wang Yujun, Xing Quanhua, Yan Jin, Senthil Maheswari, Akmal Yasir, Kowolik Claudia M, Kang Julia, Lu David M, Zhao Ming, Lin Zhixiu, Cheng Christopher H K, Yip M L Richard, Yim John H